Active Recombinant Human CXCL10 protein, Tag Free, Alexa Fluor 647 labeled

• Cat.No.: CXCL10-08H-AF647
• Product Overview: Escherichia coli expressed Human CXCL10 protein was labeled with AF647 in vitro.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Protein Length: 22-98 aa
• Description: CXCL10 also known as IP-10 is belonging to the CXC chemokine family. It is encoded by the CXCL10 gene. CXCL10 was originally identified in monocytes, endothelial cells and fibroblasts as a responsor to IFN-γ. This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3. CXCL10 has been shown to be a chemoattractant for activated T-lymphocytes and monocytes/macrophages. It also has other roles, such as promotion of T cell adhesion to endothelial cells, and inhibition of bone marrow colony formation and angiogenesis. The mouse homologue of human IP10, Crg-2, has been cloned and shown to share approximately 67 % amino acid sequence identity with human IP-10.
• Tag: Non
• Conjugation/Label: Alexa Fluor 647 labeled
• Form: Solution
• Bio-activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood T-lymphocytes is in a concentration range of 10-50 ng/ml.
• Molecular Mass: 8.6 kDa
• AA Sequence: VPLSRTVRCT CISISNQPVN PRSLEKLEII PASQFCPRVE IIATMKKKGE
  KRCLNPESKA IKNLLKAVSK EMSKRSP
• Purity: >97% by SDS-PAGE and HPLC analysis
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied.
• Concentration: 2.0 mg/mL

Gene Information

• Gene Name: CXCL10 C-X-C motif chemokine ligand 10 [ Homo sapiens (human) ]
• Official Symbol: CXCL10
• Synonyms: CXCL10; chemokine (C-X-C motif) ligand 10; INP10, SCYB10, small inducible cytokine subfamily B (Cys X Cys), member 10; C-X-C motif chemokine 10; C7; crg 2; gIP 10; IFI10; IP 10; mob 1; gamma IP10; gamma-IP10; small-inducible cytokine B10;interferon-inducible cytokine IP-10; 10 kDa interferon gamma-induced protein; protein10 from interferon (gamma)-induced cell line; small inducible cytokine subfamily B (CysX-Cys), member 10; INP10; IP-10; crg-2; mob-1; SCYB10; gIP-10
• Gene ID: 3627
• mRNA Refseq: NM_001565
• Protein Refseq: NP_001556
• MIM: 147310
• UniProt ID: P02778