Active Recombinant Human CSNK2A2 Protein, GST-His-tagged

• Cat.No.: CSNK2A2-2009H
• Product Overview: Human CSNK2A2 (NM_001896.2, 1 a.a. - 350 a.a.) full-length recombinant protein with GST-His tag expressed in Sf9 cells.

Specification

• Description: This gene encodes the alpha', or alpha 2, catalytic subunit of the protein kinase enzyme, casein kinase 2 (CK2). Casein kinase 2 is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythms. This heterotetrameric kinase includes two catalytic subunits, either alpha or alpha', and two regulatory beta subunits. The closely related gene paralog encoding the alpha, or alpha 1 subunit (CSNK2A1, Gene ID: 1457) is found on chromosome 20. An intronic variant in this gene (alpha 2) may be associated with leukocyte telomere length in a South Asian population. A related transcribed pseudogene is found on chromosome 11. [provided by RefSeq, Aug 2017]
• Source: Insect Cells
• Species: Human
• Tag: His&GST
• Form: Liquid
• Bio-activity: 2 pmol/μg x min
• Molecular Mass: 71.109 kDa
• Applications: Functional Study
  SDS-PAGE
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Concentration: 0.715 μg/μL
• Storage Buffer: In 50 mM Tris-HCl, 100 mM NaCl, pH 8.0. (5 mM DTT, 4 mM reduced glutathione, 20% glycerol)

Gene Information

• Gene Name: CSNK2A2 casein kinase 2, alpha prime polypeptide [ Homo sapiens ]
• Official Symbol: CSNK2A2
• Synonyms: CSNK2A2; casein kinase 2, alpha prime polypeptide; casein kinase II subunit alpha; CSNK2A1; CK II alpha; CK2A2; FLJ43934
• Gene ID: 1459
• mRNA Refseq: NM_001896
• Protein Refseq: NP_001887
• MIM: 115442
• UniProt ID: P19784