Active Recombinant Human CSF3R Protein, His & Avi-tagged, Biotinylated

• Cat.No.: CSF3R-5176H
• Product Overview: Biotinylated Recombinant Human CSF3R Protein (Glu 25 - Pro 621) (NP_000751), fused with an Avi tag at the C-terminus, followed by a polyhistidine tag, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&His
• Protein Length: Glu 25 - Pro 621
• Predicted N Terminal: Glu 25
• Form: Lyophilized from sterile PBS, pH7.4, 10% trehalose.
• Bio-activity: Immobilized Human G-CSF, Tag Free at 2μg/mL (100 μL/well) can bind Biotinylated Human G-CSF R with a linear range of 0.16-1.25 μg/mL.
• Molecular Mass: Recombinant Human CSF3R Protein has a calculated MW of 69.2 kDa. The protein migrates as 72-85 kDa on a SDS-PAGE gel under reducing (R) condition due to glycosylation.
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: CSF3R colony stimulating factor 3 receptor (granulocyte) [ Homo sapiens ]
• Official Symbol: CSF3R
• Synonyms: CSF3R; colony stimulating factor 3 receptor (granulocyte); CD114; granulocyte colony-stimulating factor receptor; GCSFR; G-CSF-R; CD114 antigen; G-CSF receptor
• Gene ID: 1441
• mRNA Refseq: NM_000760
• Protein Refseq: NP_000751
• MIM: 138971
• UniProt ID: Q99062
• Chromosome Location: 1p35-p34.3
• Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem; Pathways in cancer, organism-specific biosystem
• Function: cytokine receptor activity; receptor activity