Active Recombinant Human CLK1 Protein, GST-His-tagged

• Cat.No.: CLK1-1490H
• Product Overview: Human CLK1 (NM_004071.2, 1 a.a. - 484 a.a.) full-length recombinant protein with GST-His tag expressed in Sf9 cells.

Specification

• Description: This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
• Source: Insect Cells
• Species: Human
• Tag: His&GST
• Form: Liquid
• Bio-activity: 0.4 pmol/μg x min
• Molecular Mass: 86.695 kDa
• Applications: Functional Study
  SDS-PAGE
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Concentration: 0.139 μg/μL
• Storage Buffer: In 50 mM Tris-HCl, 100 mM NaCl, pH 8.0. (5 mM DTT, 4 mM reduced glutathione, 20% glycerol)

Gene Information

• Gene Name: CLK1 CDC-like kinase 1 [ Homo sapiens ]
• Official Symbol: CLK1
• Synonyms: CLK1; CDC-like kinase 1; dual specificity protein kinase CLK1; CDC28/CDC2-like kinase; protein tyrosine kinase STY; CLK; STY; CLK/STY
• Gene ID: 1195
• mRNA Refseq: NM_001162407
• Protein Refseq: NP_001155879
• MIM: 601951
• UniProt ID: P49759