Active Recombinant Human CHEK1 Protein, GST-tagged

Source :	Baculovirus-Insect Cells
Species :	Human
Tag :	GST
Predicted N Terminal :	Met
Form :	Supplied as sterile 20mM Tris, 500mM NaCl, pH 7.4, 10% glycerol, 2mM GSH.
Bio-activity :	The specific activity was determined to be 32 nmol/min/mg using CHKtide peptide (KKKVSRSGLYRSPSMPENLNRPR) as substrate.
Molecular Mass :	The recombinant human CHK1/GST chimera consists of 700 amino acids and predicts a molecular mass of 80.7kDa. It migrates as an approxiamtely 80 KDa band as predicted in SDS-PAGE under reducing conditions.
Endotoxin :	< 1.0 EU per μg of the protein as determined by the LAL method.
Purity :	>95 % as determined by SDS-PAGE.
Stability :	Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage :	Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Protein length :	1-476 a.a.

Gene Name	CHEK1 checkpoint kinase 1 [ Homo sapiens ]
Official Symbol	CHEK1
Synonyms	CHK1; CHK1 checkpoint homolog; Checkpoint, S. pombe, homolog of, 1; Chk1-S; cell cycle checkpoint kinase; checkpoint kinase-1
Gene ID	1111
mRNA Refseq	NM_001114121
Protein Refseq	NP_001107593
MIM	603078
UniProt ID	O14757
Chromosome Location	11q24.2
Pathway	Activation of ATR in response to replication stress, organism-specific biosystem; Cell cycle, conserved biosystem; DNA Double-Strand Break Repair, organism-specific biosystem