Active Recombinant Human CD27 Protein, hIgG-His-Tagged

• Cat.No.: CD27-098H
• Product Overview: Recombinant Human CD27 Protein, hIgG-His-Tagged was expressed in Baculovirus cell line

Specification

• Species: Human
• Source: Insect Cells
• Tag: His&Fc
• ProteinLength: 413aa
• Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
• Form: Liquid
• Bio-activity: Measured by its binding ability in a functional ELISA with Human CD27 Ligand. The ED50 range ≤ 0.5 ug/ml.
• Molecular Mass: 46.4 kDa
• Endotoxin: < 1 EU per 1ug of protein (determined by LAL method)
• Purity: > 85% by SDS-PAGE
• Applications: SDS-PAGE, Bioactivity
• Usage: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
• Storage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by absorbance at 280nm)
• Storage Buffer: Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Gene Information

• Gene Name: CD27 CD27 molecule [ Homo sapiens (human) ]
• Official Symbol: Cd27l
• Synonyms: CD27 antigen, CD27, S152, LPFS2, T14, TNFRSF7, Tp55, CD 27, CD27 antigen, CD27 molecule, CD27_HUMAN, CD27L receptor, LPFS2, MGC20393, OTTHUMP00000238557, S152, T cell activation antigen CD27, T cell antivation antigen S152, T-cell activation antigen CD27, T14, TNFRSF 7, TNFRSF7, TNFSF7, Tp 55,Tp55, Tumor necrosis factor receptor superfamily member 7
• Gene ID: 939
• mRNA Refseq: NM_001242.5
• Protein Refseq: NP_001233.1
• MIM: 186711
• UniProt ID: P26842