Active Recombinant Human BCHE Protein, His-Tagged

• Cat.No.: BCHE-01H
• Product Overview: Recombinant Human BCHE Protein, His-Tagged was expressed in CHO cell

Specification

• Description: This gene encodes a cholinesterase enzyme and member of the type-B carboxylesterase/lipase family of proteins. The encoded enzyme exhibits broad substrate specificity and is involved in the detoxification of poisons including organophosphate nerve agents and pesticides, and the metabolism of drugs including cocaine, heroin and aspirin. Humans homozygous for certain mutations in this gene exhibit prolonged apnea after administration of the muscle relaxant succinylcholine.
• Source: CHO
• Species: Human
• Tag: His
• Form: Liquid
• Bio-activity: Measured by its ability to cleave Butyrylthiocholine. The specific activity is >50,000 pmol/min/μg, as measured under the described conditions.
• Molecular Mass: 66 kDa
• N-terminal Sequence Analysis: Glu29
• Endotoxin: <1.0 EU per 1 μg of the protein by the LAL method.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 μg per lane.
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  6 months from date of receipt, -70 °C as supplied.
  3 months, -70 °C under sterile conditions after opening.
• Shipping: The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Gene Information

• Gene Name: BCHE butyrylcholinesterase [ Homo sapiens (human) ]
• Official Symbol: BCHE
• Synonyms: E1; CHE1; CHE2; BCHED
• Gene ID: 590
• mRNA Refseq: NM_000055.4
• Protein Refseq: NP_000046.1
• MIM: 177400
• UniProt ID: P06276