Active Recombinant Human ASS1 Protein (Full Length), N-6×His tagged

• Cat.No.: ASS1-12H
• Product Overview: Active Recombinant Human ASS1 Protein (Full Length) with N-6×His tag was expressed in E. coli.

Specification

• Description: The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of this gene cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized
• Bio-activity: The specific activity is 500 mU/mg based on its ability to convert citrulline to argininosuccinate.
• Molecular Mass: 50 kDa including tags
• Protein length: Full Length
• Purity: ≥95% SDS-PAGE
• Applications: SDS-PAGE, Functional Studies
• Storage: Store at -20 centigrade. Avoid freeze/thaw cycle.
• Storage Buffer: 0.38% Potassium phosphate, 0.46% Sodium chloride, 0.06% Tris HCl, 0.59% Potassium chloride, 0.018% (R*, R*)-1, 4-Dimercaptobutan-2, 3-diol, 0.07% EDTA, 0.107% Magnesium acetate, 1.2% BSA, 32% Trehalose, 9.6% Dextran, 1% Alcohol Ethoxylate
• Reconstitution: Reconstitute the lyophilized protein in H2O with concentration of 1.0 mU/mL. Incubate the reconstituted protein at 25 centigrade for 15 minutes.
• Shipping: Shipped at 4 centigrade.

Gene Information

• Gene Name: ASS1 argininosuccinate synthase 1 [ Homo sapiens (human) ]
• Official Symbol: ASS1
• Synonyms: ASS1; argininosuccinate synthase 1; argininosuccinate synthetase, ASS; argininosuccinate synthase; CTLN1; citrulline-aspartate ligase; citrulline--aspartate ligase; argininosuccinate synthetase 1; ASS
• Gene ID: 445
• mRNA Refseq: NM_000050
• Protein Refseq: NP_000041
• MIM: 603470
• UniProt ID: P00966