Active Recombinant Bovine HGF Protein, NK1 isoform, Animal-Free

• Cat.No.: HGF-03B
• Product Overview: Recombinant bovine HGF protein is a potent, high-purity NK1 isoform of bovine hepatocyte growth factor (HGF). Animal-free (AOF) and carrier protein-free.

Specification

• Species: Bovine
• Source: E.coli
• Description: Hepatocyte growth factor (HGF) regulates cell growth, cell motility, and morphogenesis and plays a central role in angiogenesis, tumorogenesis, and tissue regeneration. HGF binds and activates the receptor tyrosine kinase, c-Met, activating PI3K/AKT, FAK, JNK, and ERK1/2 signaling.
• Form: Lyophilized from acetonitrile, TFA
• Molecular Mass: 20 kDa
• Endotoxin: < 0.005 EU/μg protein (below level of detection)
• Purity: > 98%, by SDS-PAGE quantitative densitometry
• Applications: Differentiation of iPSCs to hepatocyte-like cells; iPSC and primary cell differentiation to muscle; Cellular agriculture and cultivated meat cell culture media optimization
• Reconstitution: Resuspend in 10mM HCl at > 100 μg/mL (provided with protein and free of charge), prepare single use aliquots, add carrier protein if desired and store frozen at -20 or -80 centigrade

Gene Information

• Gene Name: HGF hepatocyte growth factor [ Bos taurus (cattle) ]
• Official Symbol: HGF
• Synonyms: HGF; hepatocyte growth factor; hepatocyte growth factor; SF; hepapoietin A; hepatopoeitin-A; hepatopoietin-A; scatter factor
• Gene ID: 282879
• mRNA Refseq: NM_001031751
• Protein Refseq: NP_001026921
• UniProt ID: F1MZD6