Active Native Vicia Villosa Lectin Protein

• Cat.No.: Lectin-1858V
• Product Overview: This product is the Unconjugated Vicia Villosa Lectin and has sugar specificity against N-Acetylgalactosamine.

Specification

• Species: Vicia Villosa
• Source: Vicia Villosa
• Tag: Non
• Description: This lectin is a family of tetrameric glycoproteins consisting of combinations of A and B subunits similar in structure to PHA and GSL I. The dominant isolectins in our preparations appear to be B subunit-rich. VVL recognizes preferentially α- or β-linked terminal N-acetylgalactosamine, especially a single α-N-acetylgalactosamine residue linked to serine or threonine in a polypeptide (the Tn antigen). Evidence suggests that this lectin also may require specific amino acid sequences at the receptor site of glycosylation. The disaccharide galactosyl (α-1,3) N-acetylgalactosamine is also a potent inhibitor of this lectin.
• Bio-activity: Inhibiting/Eluting Sugar: 200 mM N-acetylgalactosamine
• Molecular Mass: 102 kDa - 144 kDa
• Applications: Glycobiology
• Usage: Although many buffers can be employed for reconstituting this lectin, we recommend 10 mM HEPES buffered saline, pH 8.5, 0.1 mM Ca2+. For preserving solutions stored at 4 centigrade, 0.8% sodium azide can be used.

Gene Information

• Synonyms: Lectin; VVL; VVA
• UniProt ID: P56625