Active Native Staphylococcus aureus Sphingomyelinase

• Cat.No.: Sphingomyelinase-38S
• Product Overview: Native Staphylococcus aureus Sphingomyelinase

Specification

• Species: S.aureus
• Source: S. aureus
• Description: Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine.
• Bio-activity: Specific activity: 100-300 U/mg protein. One unit will hydrolyze 1 μmol of TNPAL-sphingomyelin per minute at pH 7.4 and 37 centigrade.
• Applications: May be used exogenously to initiate the sphingomyelin signaling pathway. Has very little activity on phosphatidylcholine.
• Storage: At +4 centigrade
• Storage Buffer: Supplied in 50% glycerol/0.25 M phosphate buffer.
• Shipping: Blue Ice Not Frozen

Gene Information

• Official Symbol: Sphingomyelinase
• Synonyms: Sphingomyelinase
• UniProt ID: P09978