Active Native Human Pepsinogen I

• Cat.No.: PGA-130H
• Product Overview: Native Human Pepsinogen I was purified from Human Gastric Mucosa.

Specification

• Description: Human Pepsinogens are aspartic proteases produced in the gastric mucosa and secreted into the gastric lumen that play a major role in the digestion of proteins after activation of acidic pH. It is synthesized as isoymogens and are classified into two groups, Pepsinogen I and Pepsinogen II). Human PGA and PGC antigen have been investigated as a possible biomarker for early detection of, Gastric cancer (GC), adenoma (GA) and severe atrophic (diffuse or patchy) corpus gastritis.
• Source: Human Gastric Mucosa
• Species: Human
• Form: Lyophilized from tris-chloride, pH 8.5
• Bio-activity: > 500 U/mg protein
• Molecular Mass: 45 kDa
• Purity: > 90% (SDS-PAGE)
• Unit Definition: One unit will produce a change in A280 of 0.001 per minute at pH 2.0 and 37°C, measured as TCA-soluble products from hemoglobin.
• Stability: 3 years
• Storage: -20 centigrade
• Tag: Non