Active Native Human Cancer Antigen 72-4

• Cat.No.: CA 72-4-379H
• Product Overview: Native Human CA 72-4 was purified from Human Metastatic Liver Carcinoma.

Specification

• Species: Human
• Source: Human Metastatic Liver Carcinoma
• Tag: Non
• Description: Tumor-associated glycoprotein 72 (TAG-72) is a glycoprotein found on the surface of many cancer cells, including ovary, breast, colon, and pancreatic cells. It is a mucin-like molecule with a molar mass of over 1000 kDa. TAG-72 is a tumor marker and can be measured with radioimmunoassays like CA 72-4, which uses indium (111In) satumomab pendetide and iodine (125I) CC49 monoclonal antibody. This assay has a good specificity for gastric cancer, with a correlation to the neoplasia"s extension. It is used to identify relapses of the disease and to follow up the treatment.TAG-72 is also the target of the anti-cancer drugs anatumomab mafenatox and minretumomab.
• Form: Clear and colorless. Liquid in PBS buffer, sucrose, pH 7.4.
• Bio-activity: >100 kU/mL
• Purity: >90% (SDS-PAGE)
• Storage: Store at -20°C, Avoid repeated freeze thaw cycles.
• Preservative: 0.05% Sodium Azide