Active Native Human ANPEP protein
Cat.No. : | ANPEP-621H |
Product Overview : | Human ANPEP (967 amino acids) native protein from human serum. |
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Species : | Human |
Source : | Human |
Tag : | Non |
Description : | Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq, Jul 2008] |
Form : | Liquid |
Bio-activity : | > 500 mU/mg (L-Leu-pNA at 37°C, pH 7.2). |
Molecular Mass : | 110-130 kDa |
Purity : | > 90% by SDS-PAGE |
Applications : | Functional Study; SDS-PAGE |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | In 20 mM Tris-HCl, 500 mM NaCl, 1 mM CaCl2, pH 7.4 |
Gene Name | ANPEP alanyl (membrane) aminopeptidase [ Homo sapiens ] |
Official Symbol | ANPEP |
Synonyms | ANPEP; alanyl (membrane) aminopeptidase; CD13, PEPN; aminopeptidase N; aminopeptidase M; gp150; LAP1; microsomal aminopeptidase; p150; AP-M; AP-N; hAPN; alanyl aminopeptidase; myeloid plasma membrane glycoprotein CD13; APN; CD13; P150; PEPN; GP150; |
Gene ID | 290 |
mRNA Refseq | NM_001150 |
Protein Refseq | NP_001141 |
MIM | 151530 |
UniProt ID | P15144 |
◆ Recombinant Proteins | ||
ANPEP-247H | Recombinant Human ANPEP(Lys69-Lys967) Protein, C-6*His-tagged | +Inquiry |
ANPEP-1417H | Recombinant Human ANPEP protein, His-GST & Myc-tagged | +Inquiry |
ANPEP-694H | Active Recombinant Human ANPEP Protein, His-tagged | +Inquiry |
Anpep-1294M | Recombinant Mouse Anpep Protein, MYC/DDK-tagged | +Inquiry |
ANPEP-2657H | Recombinant Human ANPEP protein(151-230 aa), C-His-tagged | +Inquiry |
◆ Native Proteins | ||
ANPEP-621H | Active Native Human ANPEP protein | +Inquiry |
◆ Cell & Tissue Lysates | ||
ANPEP-3000MCL | Recombinant Mouse ANPEP cell lysate | +Inquiry |
ANPEP-3090HCL | Recombinant Human ANPEP cell lysate | +Inquiry |
Not For Human Consumption!
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