Active Native Galanthus Nivalis Lectin Protein, Biotinylated

• Cat.No.: Lectin-1777G
• Product Overview: This product is the Biotinylated Galanthus Nivalis Lectin and has sugar specificity against Mannose.

Specification

• Description: Galanthus nivalis lectin, unlike most mannose-specific lectins, is not a metalloprotein and does not require Ca2+ or Mn2+ for binding. Binding seems to be preferentially directed toward structures containing (α-1,3) mannose residues. Also in contrast to most mannose-binding lectins, GNL will not bind α-linked glucose. Reports indicate that this lectin binds rat and mouse IgM but not IgG. The only protein from human serum reported to bind to this lectin is α2-macroglobulin. GNL binds to many viral glycoproteins.
• Source: Galanthus nivalis
• Species: Galanthus nivalis
• Form: 10 mM HEPES, pH 7.5, 0.15 M NaCl, 0.08% sodium azide, 0.1 mM Ca2+.
• Bio-activity: Inhibiting/Eluting Sugar: 100 mM - 200 mM α-methylmannoside
• Molecular Mass: 50 kDa
• Applications: Immunohistochemistry / Immunocytochemistry, Immunofluorescence, Blotting Applications, Elispot, ELISAs, Glycobiology
• Usage: For most applications, we recommend a freshly prepared working solution of 5-20 µg/ml in the above buffer.
• Storage: Refrigerate; for long term storage, aliquots may be stored frozen. If a precipitate forms upon long-term storage, warm to 37 centigrade. and centrifuge before use
• Concentration: 2 mg/ml
• Tag: Non

Gene Information

• Synonyms: Lectin; GNL
• UniProt ID: P30617