TRA160 Antibody-coupled magnetic MicroBeads
| Cat.No. : | TRA160-5039M |
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| Species : | Human |
| Capacity : | for up to 2×10^8 total cells |
| Background : | The Anti-TRA-1-60 monoclonal antibody reacts with a pluripotent stem cell–specific antigen expressed on undifferentiated human embryonic stem (ES) cells, induced pluripotent (iPS) cells, embryonal carcinoma (EC) cells, and embryonic germ (EG) cells.2,3 The expression of TRA-1-60 on human ES cells is down-regulated upon differentiation. The Anti-TRA-1-60 antibody recognizes a neuraminidase-resistant carbohydrate epitope expressed on podocalyxin, a member of the CD34-related family of sialomucins. Podocalyxin is a transmembrane glycoprotein, which has been implicated in the development of aggressiveness in a variety of cancers including breast cancer and prostate cancer. |
| Application : | Positive selection of undifferentiated TRA-1-60+ pluripotent stem cells, for example, human ES and iPS cells. Efficient enrichment of iPS cells during or after reprogramming. |
Not For Human Consumption!
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