TFRC
-
Official Full Name
transferrin receptor -
Overview
Transferrin receptor protein 1 (TfR1) also known as (Cluster of Differentiation 71) (CD71) is a protein that in humans is encoded by the TFRC gene. TfR1 is required for iron delivery from transferrin to cells -
Synonyms
TFRC;transferrin receptor;T9;TR;TFR;p90;CD71;TFR1;TRFR
Recombinant Proteins
- Human
- Marmoset
- Cynomolgus/Rhesus
- Cynomolgus
- Horse
- Chicken
- Mouse
- Pig
- Rat
- Mammalian cells
- HEK293
- Insect Cell
- Human Cell
- E.coli
- Mammalian Cell
- HEK293F
- Human plasma
- 293F
- Human Serum
- E. coli
- Baculovirus
- HEK293T
- Human Plasma
- His
- His&GST
- His&S
- Non
- Fc
- His&Avi
- N-His-Avi
- His&Fc&Avi
- FLAG
- N-His-SUMO
- Myc&DDK
- Flag
Involved Pathway
TFRC involved in several pathways and played different roles in them. We selected most pathways TFRC participated on our site, such as HIF- signaling pathway,Endocytosis,Phagosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with TFRC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hematopoietic cell lineage | CD2,EPO,Itga10&Itgb1,ITGA4,FLT3,CD5,CD8B,DNTT,GM13305,IL5 |
| Phagosome | ITGB1,RAC1A,SFTPA1,THBS3,ATP6V0E1,Cd209g,SEC61AL2,TLR2,HLA-DQA1,MHC1UXA2 |
| Endocytosis | HLA-B,EPN1,CXCR1,IL2RGA,ARAP2,FOLR2,ARPC1B,RAB5AB,RAB8A,ARPC5A |
| HIF- signaling pathway | ANGPT2,PFKFB3,IFNGR1,MAP2K2,TCEB1,PIK3CA,EIF4E2,TEK,GAPDH,INS1 |
Protein Function
TFRC has several biochemical functions, for example, Hsp70 protein binding,chaperone binding,double-stranded RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TFRC itself. We selected most functions TFRC had, and list some proteins which have the same functions with TFRC. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| virus receptor activity | PVRL2,CR1,CD86,SELPLG,HSPA1A,XPR1,SLC52A2,SIVA1,SERPINB3,TNFRSF4 |
| protein binding | KBTBD7,CHRNA5,ADI1,CUL3,RAB1B,GCG,TCTN2,SPRED2,B3GAT3,FDXR |
| identical protein binding | CEACAM5,C1QTNF2,MVK,APPL1,IFI203,PPPDE2,C1QTNF9,DES,DYNLT1A,PFKL |
| transferrin transmembrane transporter activity | SLC11A2 |
| chaperone binding | PACRG,TIMM10,TBCE,CDC37,HSP104,HSPE1,AMFR,DNAJB7,PIH1D3,DNAJA3A |
| Hsp70 protein binding | RNF207,GPR37,CDKN1B,MVD,DNAJB2,CDK1,RPS3,L7RN6,PPID,FAM119A |
| double-stranded RNA binding | VIM,OASL2,ACTN1,OAS2,TLR8,STAU2,STRBP,OAS1A,DGCR8,EIF4A1 |
| transferrin receptor activity | TFR2,TFR1B,TFR1A |
| poly(A) RNA binding | NOA1,PRPF3,CSNK1E,RSL1D1,CDC40,MRM1,NOP2,MFAP1B,RPL35A,DARS |
Interacting Protein
TFRC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TFRC here. Most of them are supplied by our site. Hope this information will be useful for your research of TFRC.
SH3BP4;HFE;SGTA;ALB;ERBB2;VCAM1
Resources
Research Area
Mesenchymal Stem Cell MarkersEpithelial Cell Markers and Intracellular Molecules
Mesodermal Lineage Markers
MDSC Phenotyping - Positive Markers
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References
