OCLN
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Official Full Name
occludin -
Overview
This gene encodes an integral membrane protein which is located at tight junctions. This protein may be involved in the formation and maintenance of the tight junction. The possibility of several alternatively spliced products has been suggested but the full nature of these products has not been described. -
Synonyms
OCLN;occludin;tight junction protein occludin TM4 minus;tight junction protein occludin;BLCPMG;FLJ08163;FLJ18079;FLJ77961;FLJ94056;MGC34277
Recombinant Proteins
- Human
- Rat
- Chicken
- Mouse
- Dog
- Mus musculus
- Xenopus laevis
- Potorous tridactylus (Potoroo)
- Pongo Abelii
- E.coli
- Wheat Germ
- HEK293
- Mammalian Cell
- In Vitro Cell Free System
- HEK293T
- Mamanlian cells
- E.coli expression system
- GST
- Non
- Myc&DDK
- His
- His&Fc&Avi
- Flag
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| OCLN-1440H | Recombinant Human OCLN, GST-tagged | E.coli | Human | GST | 269-522aa | |
| OCLN-27766TH | Recombinant Human OCLN | Wheat Germ | Human | Non | 522 amino acids |
|
| OCLN-27768TH | Recombinant Human OCLN | Wheat Germ | Human | Non | 100 amino acids |
|
| OCLN-3603H | Recombinant Human OCLN protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
|
|
| OCLN-4153R | Recombinant Rat OCLN Protein | Mammalian Cell | Rat | His |
|
|
| OCLN-6685C | Recombinant Chicken OCLN | Mammalian Cell | Chicken | His |
|
|
| OCLN-3603HCL | Recombinant Human OCLN 293 Cell Lysate | HEK293 | Human | Non |
|
|
| Ocln-1882M | Recombinant Mouse Ocln Protein, His-tagged | E.coli | Mouse | His | Lys264-Pro521 |
|
| OCLN-2523H | Recombinant Human OCLN Protein, His-tagged | E.coli | Human | His | Lys266-Thr522 |
|
| OCLN-352HF | Recombinant Full Length Human OCLN Protein | In Vitro Cell Free System | Human | Full L. 522 amino acids |
|
|
| OCLN-3815R | Recombinant Rat OCLN Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
|
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| OCLN-3815R-B | Recombinant Rat OCLN Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
|
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| OCLN-3859H | Recombinant Human OCLN Protein (Lys266-Thr522), His tagged | E.coli | Human | His | Lys266-Thr522 |
|
| Ocln-425M | Recombinant Mouse Ocln Protein, His-tagged | E.coli | Mouse | His | Phe17~Ser107 |
|
| Ocln-4569M | Recombinant Mouse Ocln Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
|
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| OCLN-9487HFL | Recombinant Full Length Human OCLN protein, Flag-tagged | Mamanlian cells | Human | Flag | Full L. |
|
| RFL15045CF | Recombinant Full Length Dog Occludin(Ocln) Protein, His-Tagged | E.coli expression system | Dog | His | Full L. Full Length (1-521) |
|
| RFL15777MF | Recombinant Full Length Mouse Occludin(Ocln) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length (1-521) |
|
| RFL1932XF | Recombinant Full Length Xenopus Laevis Occludin(Ocln) Protein, His-Tagged | E.coli expression system | Xenopus laevis | His | Full L. Full Length (1-493) |
|
| RFL2330RF | Recombinant Full Length Rat Occludin(Ocln) Protein, His-Tagged | E.coli expression system | Rat | His | Full L. Full Length (1-523) |
|
| RFL27577GF | Recombinant Full Length Chicken Occludin(Ocln) Protein, His-Tagged | E.coli expression system | Chicken | His | Full L. Full Length (1-504) |
|
| RFL33863HF | Recombinant Full Length Human Occludin(Ocln) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-522) |
|
| RFL35773PF | Recombinant Full Length Potorous Tridactylus Occludin(Ocln) Protein, His-Tagged | E.coli expression system | Potorous tridactylus (Potoroo) | His | Full L. Full Length (1-489) |
|
| RFL6522PF | Recombinant Full Length Pongo Abelii Occludin(Ocln) Protein, His-Tagged | E.coli expression system | Pongo Abelii | His | Full L. Full Length (1-522) |
|
Involved Pathway
OCLN involved in several pathways and played different roles in them. We selected most pathways OCLN participated on our site, such as Apoptosis,Apoptotic cleavage of cell adhesion proteins,Apoptotic cleavage of cellular proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with OCLN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Apoptotic cleavage of cellular proteins | DSG3,DSG1,VIML,CASP6L2,DSP,PTBP3,STK24,LMNB1,SPNA2,SATB1 |
| Cell adhesion molecules (CAMs) | CD80,NLGN3A,CLDN15A,L1CAM,ICAM2,CDH1,SELP,ITGB1,ITGA6B,CLDNE |
| Hepatitis C | IFNA10,PPP2R2C,CLDN23,MAPK1,MAPK8,CD81,PDPK1,NR1H3,TRAF2,IFNA5 |
| Leukocyte transendothelial migration | MAPK13,NCF1,NIPAL1,VAV2,RAP1B,ARHGAP35,CYBB,PIK3CD,ICAM1,ACTN1 |
| Apoptosis | NTRK1,IRAK1,PIK3R3A,IKBKG,CDKN2A,IRF6,BAXA,PRKAR2AB,BAX,BIDA |
| Apoptotic execution phase | ADD1,PKP1,SATB1,DSG2,DSP,DBNLB,DNM1L,VIML,DFFA,HIST1H1E |
| Apoptotic cleavage of cell adhesion proteins | DSG1,DSG2,CTNNB2,PKP1,CTNNB1,PTBP3,DSP,DSG3 |
| Pathogenic Escherichia coli infection | KRT18,TUBB,PRKCA,ITGB1,TUBB1,TUBA1A,FYN,TUBA3E,TLR5,WAS |
Protein Function
OCLN has several biochemical functions, for example, protein binding,protein domain specific binding,thiopurine S-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by OCLN itself. We selected most functions OCLN had, and list some proteins which have the same functions with OCLN. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PTPRM,PLEKHN1,GPRASP1,OBFC1,TMA16,MCM4,IRAK4,APOL1,EIF5A,DDX58 |
| protein domain specific binding | DBNL,EZR,PRKCI,HIST1H4N,TADA3,ITGA3,HOMER3,CASP2,EFS,TWIST2 |
| thiopurine S-methyltransferase activity | TPMT,TPMT.2,TPMT.1 |
Interacting Protein
OCLN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OCLN here. Most of them are supplied by our site. Hope this information will be useful for your research of OCLN.
CSNK1E;SYNE4;CLEC7A;PLSCR1;CSNK1A1;TJP1;ULK1;SNW1
Resources
Research Area
Tight Junction Proteins in Endothelial CellsTight Junction Proteins in VSMC
Epithelial Cell Markers and Intracellular Molecules
gamma delta T Cells
Tight Junctions
Related Services
Related Products
References
- Bankwitz, D; Vieyres, G; et al. Role of Hypervariable Region 1 for the Interplay of Hepatitis C Virus with Entry Factors and Lipoproteins. JOURNAL OF VIROLOGY 88:12644-12655(2014).
- Haid, S; Grethe, C; et al. Isolate-Dependent Use of Claudins for Cell Entry by Hepatitis C Virus. HEPATOLOGY 59:24-34(2014).
