NME4
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Official Full Name
non-metastatic cells 4, protein expressed in -
Overview
The nucleoside diphosphate (NDP) kinases (EC 2.7.4.6) are ubiquitous enzymes that catalyze transfer of;gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates.;The enzymes are products of the nm23 gene family, which includes NME4 (Milon et al., 1997 (PubMed 9099850)). -
Synonyms
NME4;non-metastatic cells 4, protein expressed in;nucleoside diphosphate kinase, mitochondrial;nm23 H4;NM23H4;NDK;NDPKD;NDP kinase D;NDP kinase, mitochondrial;nucleoside diphosphate kinase D;NDPK-D;nm23-H4
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rhesus macaque
- Chicken
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- Non
- His&T7
- His&Fc&Avi
- Myc&DDK
Involved Pathway
NME4 involved in several pathways and played different roles in them. We selected most pathways NME4 participated on our site, such as Purine metabolism,Pyrimidine metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with NME4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | UCK2A,CMPK1,PKMA,CYP2A12,EXT1C,ATP6V0E1,PTGDS,B3GNT6,PAH,B3GNT1 |
| Purine metabolism | APRT,URAD,PNP5B,ENTPD5,POLR2J2,ADKB,PDE4A,ENPP4,POLE,GUCY1A3 |
| Pyrimidine metabolism | UPRT,POLR3B,CANT1B,NME1-NME2,POLE2,POLR1A,POLE,POLR2L,TWISTNB,POLD2 |
Protein Function
NME4 has several biochemical functions, for example, ATP binding,lipid binding,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NME4 itself. We selected most functions NME4 had, and list some proteins which have the same functions with NME4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| lipid binding | APOA1B,ANXA6,LTC4S,CYP21A1,SH3GLB1,Ar,FABP9,RBP2A,APOEB,SNX10A |
| ATP binding | TTF2,GALK2,CKMB,AKT2L,RIOK1,CDK2,LIMK2,ULK3,TTBK1,SLC27A5 |
| protein binding | STX12,IFNA4,ZC3H12A,LSM5,HIST1H1E,SS18,CCDC109A,PARN,ERCC8,NR3C1 |
| nucleoside diphosphate kinase activity | NME2B.2,NME5,NME2B.1,NME7,NME3,NME8,CMPK2,AK1,NME9,TXNDC3 |
| metal ion binding | ZNF263,GYG1,FAH,ACVR1B,ZNF480,ANG3,TPH1A,ATP2B2,ITK,HBBE2 |
Interacting Protein
NME4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NME4 here. Most of them are supplied by our site. Hope this information will be useful for your research of NME4.
NME1;CLNK;TNS4;HTT;SOCS3;LSM8;NME2;TRIP13;SUV39H2;ssrna_au;NSS;ICT1
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