MPV17
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Official Full Name
MpV17 mitochondrial inner membrane protein -
Overview
This gene encodes a mitochondrial inner membrane protein that is implicated in the metabolism of reactive oxygen species. Mutations in this gene have been associated with the hepatocerebral form of mitochondrial DNA depletion syndrome (MDDS). -
Synonyms
MPV17;MpV17 mitochondrial inner membrane protein;MpV17 transgene, murine homolog, glomerulosclerosis;protein Mpv17;glomerulosclerosis;SYM1;Mpv17 human homolog of glomerulosclerosis and nephrotic syndrome;MPV17_HUMAN;MTDPS6;Mpv17, human homolog of glomerulosclerosis and nephrotic syndrome
Recombinant Proteins
- Mouse
- Zebrafish
- Rhesus macaque
- Human
- zebrafish
- Mus musculus
- Bovine
- Xenopus laevis
- Rat
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- E.coli
- His
- Non
- His&Fc&Avi
- GST
- His&SUMO
Involved Pathway
MPV17 involved in several pathways and played different roles in them. We selected most pathways MPV17 participated on our site, such as Peroxisome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MPV17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Peroxisome | ACSL4,ANI_1_2390104,PEX11B,MPV17L2,ACOX3,SCP2,NUDT19,PEX5L,PEX26,ABCD3 |
Protein Function
MPV17 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by MPV17 itself. We selected most functions MPV17 had, and list some proteins which have the same functions with MPV17. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | CHCHD6A,LINS,LRRD1,TMEM30C,THADA,PHLDB1,MORC4,ODF2L,SLC15A5,TBC1D8 |
Interacting Protein
MPV17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MPV17 here. Most of them are supplied by our site. Hope this information will be useful for your research of MPV17.
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References
- Binder, CJ; Weiher, H; et al. Glomerular overproduction of oxygen radicals in Mpv17 gene-inactivated mice causes podocyte foot process flattening and proteinuria - A model of steroid-resistant nephrosis sensitive to radical scavenger therapy. AMERICAN JOURNAL OF PATHOLOGY 154:1067-1075(1999).
