GRAP2
-
Official Full Name
GRB2-related adaptor protein 2 -
Overview
This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist. -
Synonyms
GRAP2;GRB2-related adaptor protein 2;GRB2-related adapter protein 2;GADS;GRBLG;GrbX;Grf40;Mona;grf-40;GRB-2-like protein;adapter protein GRID;grf40 adapter protein;SH3-SH2-SH3 adapter Mona;SH3-SH2-SH3 adaptor molecule;growth factor receptor-binding protein;GRB2-related protein with insert domain;hematopoietic cell-associated adapter protein GrpL;hematopoietic cell-associated adaptor protein GRPL;growth factor receptor-bound protein 2-related adaptor protein 2;P38;GRID;GRPL;GRB2L;GRAP-2
Recombinant Proteins
- Human
- Rhesus macaque
- Mouse
- Rat
- E.coli
- Mammalian Cell
- E. coli
- HEK293
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- Non
- His&T7
- His&Fc&Avi
- Myc&DDK
Involved Pathway
GRAP2 involved in several pathways and played different roles in them. We selected most pathways GRAP2 participated on our site, such as T cell receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRAP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| T cell receptor signaling pathway | MAPK9,Il2,CD40LG,PIK3R5,EVLB,NFKB1,PDCD1,MUC1,CD8B1,PAK7 |
Protein Function
GRAP2 has several biochemical functions, for example, chloride channel activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GRAP2 itself. We selected most functions GRAP2 had, and list some proteins which have the same functions with GRAP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chloride channel activity | GABRP,GABRA5,CLCA5,SLC1A4,SLC26A1,GABRA3,CLCA3,APOL1,SLC26A4,CLCC1 |
| protein binding | KRTAP12-1,NTF4,TTC8,PLK1,CHERP,ZNF10,BMPR1AA,SPSB1,SF3A3,CD70 |
Interacting Protein
GRAP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRAP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GRAP2.
LCP2;PTPN23
Resources
Related Services
Related Products
References
