GJA3
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Official Full Name
gap junction protein, alpha 3, 46kDa -
Overview
The protein encoded by this gene is a connexin and is a component of lens fiber gap junctions. Defects in this gene are a cause of zonular pulverulent cataract type 3 (CZP3). -
Synonyms
GJA3;gap junction protein, alpha 3, 46kDa;CZP3, gap junction protein, alpha 3, 46kD (connexin 46) , gap junction protein, alpha 3, 46kDa (connexin 46);gap junction alpha-3 protein;connexin 46;CX46;connexin-46;CZP3
Recombinant Proteins
- Zebrafish
- Rat
- Chicken
- Bovine
- Human
- Sheep
- Mus musculus
- Mammalian Cells
- HEK293
- E.coli
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GJA3-11837Z | Recombinant Zebrafish GJA3 | Mammalian Cells | Zebrafish | His |
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| GJA3-2546R | Recombinant Rat GJA3 Protein | Mammalian Cells | Rat | His |
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| GJA3-3420C | Recombinant Chicken GJA3 | Mammalian Cells | Chicken | His |
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| GJA3-2202R | Recombinant Rat GJA3 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| GJA3-2202R-B | Recombinant Rat GJA3 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| RFL21593GF | Recombinant Full Length Chicken Gap Junction Alpha-3 Protein(Gja3) Protein, His-Tagged | E.coli | Chicken | His | Full L. Full Length of Mature Protein (2-511) |
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| RFL22287BF | Recombinant Full Length Bovine Gap Junction Alpha-3 Protein(Gja3) Protein, His-Tagged | E.coli | Bovine | His | Full L. Full Length of Mature Protein (2-407) |
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| RFL23425HF | Recombinant Full Length Human Gap Junction Alpha-3 Protein(Gja3) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length of Mature Protein (2-435) |
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| RFL2375RF | Recombinant Full Length Rat Gap Junction Alpha-3 Protein(Gja3) Protein, His-Tagged | E.coli | Rat | His | Full L. Full Length of Mature Protein (2-416) |
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| RFL29042OF | Recombinant Full Length Sheep Gap Junction Alpha-3 Protein(Gja3) Protein, His-Tagged | E.coli | Sheep | His | Full L. Full Length of Mature Protein (2-413) |
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| RFL4305MF | Recombinant Full Length Mouse Gap Junction Alpha-3 Protein(Gja3) Protein, His-Tagged | E.coli | Mus musculus | His | Full L. Full Length of Mature Protein (2-417) |
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Involved Pathway
GJA3 involved in several pathways and played different roles in them. We selected most pathways GJA3 participated on our site, such as Calcium Regulation in the Cardiac Cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with GJA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Calcium Regulation in the Cardiac Cell | GNB5B,RGS14,CASQ1,CX34.4,ADRA1B,RGS17,ADRB1,YWHAQ,GNB3B,GJB1 |
Protein Function
GJA3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by GJA3 itself. We selected most functions GJA3 had, and list some proteins which have the same functions with GJA3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
GJA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GJA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GJA3.
Resources
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References
- Yuan, LM; Guo, Y; et al. Identification of a Novel GJA3 Mutation in Congenital Nuclear Cataract. OPTOMETRY AND VISION SCIENCE 92:337-342(2015).
- Inoue, A; Okamoto, K; et al. B-RAF mutation and accumulated gene methylation in aberrant crypt foci (ACF), sessile serrated adenoma/polyp (SSA/P) and cancer in SSA/P. BRITISH JOURNAL OF CANCER 112:403-412(2015).
