Ephb1
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Official Full Name
EPH receptor B1 -
Overview
The Eph receptors are the largest known family of receptor tyrosine kinases (RTKs). They can be divided into two groups based on sequence similarity and on their preference for a subset of ligands: EphA receptors bind to a glycosylphosphatidylinositol-anc -
Synonyms
EPHB1;EPH receptor B1;EphB1 , EPHT2;ephrin type-B receptor 1;Hek6;EK6;EPH-like kinase 6;eph tyrosine kinase 2;soluble EPHB1 variant 1;tyrosine-protein kinase receptor EPH-2;neuronally-expressed EPH-related tyrosine kinase;ELK;NET;EPHT2;FLJ37
Recombinant Proteins
- Human
- Mouse
- Rat
- Rhesus macaque
- Cynomolgus
- E.coli
- HEK293
- Insect Cells
- Sf9 Cells
- Mammalian Cells
- Wheat Germ
- Human Cells
- GST
- His
- GST&His
- Fc
- Flag&His
- Flag
- Fc&His
- Non
- Avi&Fc&His
Involved Pathway
Ephb1 involved in several pathways and played different roles in them. We selected most pathways Ephb1 participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ephb1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Axon guidance | EZRA,EVL,SEMA6D,DUSP2,SPRED3,KALRNB,FGF8B,CLTA,NRTN,SEMA4D |
Protein Function
Ephb1 has several biochemical functions, for example, ATP binding,axon guidance receptor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ephb1 itself. We selected most functions Ephb1 had, and list some proteins which have the same functions with Ephb1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CNO,E2F6,ATG16L1,DROSHA,TAF1B,RXFP4,NXT2,BCAR1,GTF2H2,GPRIN2 |
| axon guidance receptor activity | EPHB3,ROBO2,GFRA3,ROBO1,SEMA5A,EPHA7 |
| ATP binding | GLULC,MAPK12B,ERN2,SGK196,KATNAL1,SLFNL1,MYH6,CSNK1G1,TNIK,MAPK11 |
| transmembrane-ephrin receptor activity | EPHA4,EPHA5,EFNA3,EPHB2,EFNB3,EFNA4,EPHA10,EPHA1 |
| protein complex binding | PPARA,PPP2R2A,BCAP31,FADD,CAV3,BRK1,MLC1,DISC1,RBX1,RRAS |
Interacting Protein
Ephb1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ephb1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ephb1.
GRB7;GRB2;GRB10;HSP90AB1;Grb2;Grb10;Nck1;bosutinib;dasatinib;purvalanol b;NCK1
Resources
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References
- Zhou, SG; Wang, LX; et al. Decreased expression of receptor tyrosine kinase of EphB1 protein in renal cell carcinomas. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY 7:4254-4260(2014).
- Li, WL; Mukouyama, YS; et al. Tissue-specific venous expression of the EPH family receptor EphB1 in the skin vasculature. DEVELOPMENTAL DYNAMICS 242:976-988(2013).
