ENOPH1
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Official Full Name
enolase-phosphatase 1 -
Overview
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). -
Synonyms
ENOPH1;enolase-phosphatase 1;enolase-phosphatase E1;acireductone synthase;E1;Enolase phosphatase E1;MASA;2 3 diketo 5 methylthio 1 phosphopentane phosphatase;2;3-diketo-5-methylthio-1-phosphopentane phosphatase;DKFZp586M0524;E 1 enzyme;Enolase phosphatase 1;ENOPH_HUMAN;FLJ12594;MASA homolog;MST145;MSTP145 protein;OTTHUMP00000160806;OTTHUMP00000219541;2,3-diketo-5-methylthio-1-phosphopentane phosphatase
Recombinant Proteins
- Human
- Rat
- Zebrafish
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- Avi
- Fc
- DDK
- Myc
- GST
Involved Pathway
ENOPH1 involved in several pathways and played different roles in them. We selected most pathways ENOPH1 participated on our site, such as Cysteine and methionine metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ENOPH1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cysteine and methionine metabolism | LDHA,AHCYL2,MAT2B,MRI1,GOT2B,GCLC,DNMT3B,AHCY,GOT2A,DNMT3AA |
| Metabolic pathways | PLA2G4A,LASS2,IMPDH2,CHKA,HMGCRB,UGT1A6,GLCEB,RRM2,HYI,PTGDSB |
Protein Function
ENOPH1 has several biochemical functions, for example, acireductone synthase activity,hydrolase activity,magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ENOPH1 itself. We selected most functions ENOPH1 had, and list some proteins which have the same functions with ENOPH1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| magnesium ion binding | PPM1NB,FEN1,IDH1,RPS6KA3B,NLK,ABL1,ZNF143B,ALPI,RRAGC,STK38L |
| metal ion binding | ENPP5,PRIM2,ASH2L,EBF4,XRCC6BP1,LHX8,PARN,ZFP628,ZFP184,ZNF471 |
| hydrolase activity | ABHD8,CNOT6L,DPYSL2B,C6AST3,ATP6V0E,OTUD7A,TDRD12,ACY3.2,ACOT10,PPAPDC3 |
Interacting Protein
ENOPH1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ENOPH1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ENOPH1.
Ywhae
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References
- Nakano, T; Ohki, I; et al. MtnBD Is a Multifunctional Fusion Enzyme in the Methionine Salvage Pathway of Tetrahymena thermophila. PLOS ONE 8:-(2013).
- Mary, C; Duek, P; et al. Functional Identification of APIP as Human mtnB, a Key Enzyme in the Methionine Salvage Pathway. PLOS ONE 7:-(2012).
