E-Cadherin
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Official Full Name
cadherin 1, type 1, E-cadherin (epithelial) -
Overview
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production. -
Synonyms
Arc1;CADH1_HUMAN;Cadherin 1;cadherin 1 type 1 E-cadherin;Cadherin1;CAM 120/80;CD 234;CD324;CD324 antigen;CDH1;CDHE;E-Cad/CTF3;E-cadherin;ECAD;Epithelial cadherin;epithelial calcium dependant adhesion protein;LCAM;Liver cell adhesion molecule;UVO;Uvomorulin;E-Cadherin;cadherin 1, type 1, E-cadherin (epithelial)
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Involved Pathway
E-Cadherin involved in several pathways and played different roles in them. We selected most pathways E-Cadherin participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with E-Cadherin were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
E-Cadherin has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by E-Cadherin itself. We selected most functions E-Cadherin had, and list some proteins which have the same functions with E-Cadherin. You can find most of the proteins on our site.
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Interacting Protein
E-Cadherin has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with E-Cadherin here. Most of them are supplied by our site. Hope this information will be useful for your research of E-Cadherin.
Resources
Research Area
Tumor SuppressorsHemangioblast Markers
Other CD Antigen
Natural Killer Cell (NK Cell)
Embryonic and Induced Pluripotent Stem Cell Markers
Adherens Junction Proteins in Endothelial Cells
Epithelial Cell Markers and Intracellular Molecules
Mesenchymal to Epithelial Transition
Langerhans and Dermal Dendritic Cells
gamma delta T Cells
Cadherin Superfamily
Microfilament-associated Proteins
Mesodermal Lineage Markers
Cadherins
Adherens Junctions
Melanoma Biomarkers
Related Services
Related Products
References
