ARHGAP1

  • Official Full Name

    Rho GTPase activating protein 1

  • Overview

    Rho GTPase-activating protein 1 is an enzyme that in humans is encoded by the ARHGAP1 gene.

  • Synonyms

    ARHGAP1;Rho GTPase activating protein 1;rho GTPase-activating protein 1;Cdc42GAP;p50rhoGAP;RhoGAP;ARHGAP 1;CDC42 GTPase activating protein;GTPase activating protein rhoOGAP;OTTHUMP00000233485;OTTHUMP00000233486;p50 RhoGAP;Rho related small GTPase protein activator;Rho type GTPase activating protein 1;RHOGAP1;p50-RhoGAP;CDC42 GTPase-activating protein;GTPase-activating protein rhoOGAP;rho-type GTPase-activating protein 1;rho-related small GTPase protein activator

Recombinant Proteins

  • Human
  • Zebrafish
  • Rhesus macaque
  • Mouse
  • E.coli
  • Mammalian Cell
  • HEK293
  • HEK293T
  • Mammalian cells
  • Wheat Germ
  • GST
  • His
  • Non
  • Myc&DDK
  • Flag
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
ARHGAP1-9812H Recombinant Human ARHGAP1, GST-tagged E.coli Human GST C-term-350a.a.
ARHGAP1-36H Active Recombinant Human ARHGAP1 protein, GST-tagged E.coli Human GST
ARHGAP1-2523Z Recombinant Zebrafish ARHGAP1 Mammalian Cell Zebrafish His
ARHGAP1-387R Recombinant Rhesus monkey ARHGAP1 Protein, His-tagged Mammalian Cell Rhesus macaque His
ARHGAP1-8745HCL Recombinant Human ARHGAP1 293 Cell Lysate HEK293 Human Non
Arhgap1-1678M Recombinant Mouse Arhgap1 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
ARHGAP1-2058HFL Recombinant Full Length Human ARHGAP1 Protein, C-Flag-tagged Mammalian cells Human Flag Full L.
ARHGAP1-216R Recombinant Rhesus Macaque ARHGAP1 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
ARHGAP1-216R-B Recombinant Rhesus Macaque ARHGAP1 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
ARHGAP1-26235TH Recombinant Human ARHGAP1 Wheat Germ Human Non 100 amino acids
ARHGAP1-373H Recombinant Human ARHGAP1 Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
ARHGAP1-373H-B Recombinant Human ARHGAP1 Protein Pre-coupled Magnetic Beads HEK293 Human
ARHGAP1-37H Active Recombinant Human ARHGAP1 Protein (Full Length), N-His tagged E.coli Human His Full L. Full Length

    Involved Pathway

    ARHGAP1 involved in several pathways and played different roles in them. We selected most pathways ARHGAP1 participated on our site, such as Regulation of CDC42 activity,Regulation of RAC1 activity,Rho GTPase cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARHGAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Rho GTPase cycle RHOF,DCLRE1B,ARHGAP31,ARHGAP24,GDI1,ARHGAP28,STARD13,ARHGAP18,ARHGEF18,ARAP2
    Regulation of CDC42 activity DOCK9,BCAR3,DOCK10,ARHGAP17,ITSN2,RALBP1,ARHGEF25,DOCK6,DNMBP,MCF2L
    Signal Transduction CRABP1A,ARHGAP20,ARHGAP29,IQCE,WWOX,OTULIN,RTKN,PNOCB,SKIA,USP34
    Regulation of RAC1 activity EPS8,ARHGAP17,RALBP1,ARHGAP9,DOCK6,CHN2,CHN1,RAP1GDS1,ABR,DEF6
    Signaling by Rho GTPases ARHGAP44,ARHGAP10,RHOT2,TAGAPA,NF2A,RHPN2,ARHGAP18,ARHGEF16,FMNL1,ARHGAP25

    Protein Function

    ARHGAP1 has several biochemical functions, for example, GTPase activator activity,SH3 domain binding,SH3/SH2 adaptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ARHGAP1 itself. We selected most functions ARHGAP1 had, and list some proteins which have the same functions with ARHGAP1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding CNPY2,DAZL,SYMPK,TWIST1,C1orf38,PIAS2,ADIPOQ,OLFM2,TMEM140,TAC1
    GTPase activator activity ARHGAP22,ARFGAP2,RANGAP1A,TBC1D8,RABEP2,RGS11,TBC1D14,TBC1D19,DEPDC1B,TBC1D9B
    SH3/SH2 adaptor activity KHDRBS1,SKAP2,BLNK,PTPN11,SH2D2A,CHN1,LASP1,ARHGAP4,CRKL,LAT
    SH3 domain binding ARHGAP6,AFAP1L2,ARHGAP27,RAD9A,FAM125A,SH3BGRL2,ELMO3,GRIK5,MAPK15,WIPF3

    Interacting Protein

    ARHGAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARHGAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARHGAP1.

    CDC42;RHOA;CDC42;CHEK2;RHOC;AGTRAP;q8d0i9_yerpe;pi3p;1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate;ere_dna;STK4

    Resources

    References

    • Jarius, S; Scharf, M; et al. Antibodies to the inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) in cerebellar ataxia. Journal of Neuroinflammation 11:-(2014).
    • Navarrete-Perea, J; Moguel, B; et al. Identification and quantification of host proteins in the vesicular fluid of porcine Taenia solium cysticerci. EXPERIMENTAL PARASITOLOGY 143:11-17(2014).

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