AICDA
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Official Full Name
activation-induced cytidine deaminase -
Overview
Activation-induced cytidine deaminase (AID) is thought to modify RNA due to its high homology to the RNA editing enzyme APOBEC-1. This function, however, has not been confirmed in in vitro studies, which show that AID has significant cytidine deaminase ac -
Synonyms
AICDA;activation-induced cytidine deaminase;cytidine aminohydrolase;activation induced deaminase;Aid;Arp2
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Chicken
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- Yeast
- Insect Cell
- In Vitro Cell Free System
- Non
- His
- GST
- His&Myc
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| AICDA-1565H | Recombinant Human AICDA protein | E.coli | Human | Non | ||
| AICDA-9502H | Recombinant Human AICDA, His-tagged | E.coli | Human | His | 1-198a.a. | |
| AICDA-1447M | Recombinant Mouse AICDA Protein | Mammalian Cell | Mouse | His |
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| Aicda-1566M | Recombinant Mouse Aicda protein | E.coli | Mouse | Non |
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| AICDA-1868Z | Recombinant Zebrafish AICDA | Mammalian Cell | Zebrafish | His |
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| AICDA-4514C | Recombinant Chicken AICDA | Mammalian Cell | Chicken | His |
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| AICDA-471H | Recombinant Human AICDA Protein, GST-tagged | Wheat Germ | Human | GST |
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| AICDA-7113H | Recombinant Human AICDA, His-tagged | E.coli | Human | His | 1-198aa |
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| AICDA-8958HCL | Recombinant Human AICDA 293 Cell Lysate | HEK293 | Human | Non |
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| AICDA-0089H | Recombinant Human AICDA Protein (Gly23-Leu183), N-His-tagged | E.coli | Human | His | Gly23-Leu183 |
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| Aicda-1248M | Recombinant Mouse Aicda protein, His-tagged | Yeast | Mouse | His | 1-198aa |
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| AICDA-2195H | Recombinant Human AICDA protein, His&Myc-tagged | Yeast | Human | His&Myc | 1-198aa |
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| Aicda-2495M | Recombinant Mouse Aicda protein, His&Myc-tagged | E.coli | Mouse | His&Myc | 1-198aa |
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| AICDA-2783H | Recombinant Human AICDA Protein (1-198 aa), His-Myc-tagged | Insect Cell | Human | His&Myc | 1-198 aa |
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| AICDA-409M | Recombinant Mouse AICDA Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| AICDA-409M-B | Recombinant Mouse AICDA Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| AICDA-953HF | Recombinant Full Length Human AICDA Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 198 amino acids |
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Involved Pathway
AICDA involved in several pathways and played different roles in them. We selected most pathways AICDA participated on our site, such as Intestinal i,ne network for IgA production,Primary i, which may be useful for your reference. Also, other proteins which involved in the same pathway with AICDA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| ne network for IgA production | CXCL12B,Icosl,CCL27B,CXCR4,HLA-DQA2,IL5,MADCAM1,TNFSF13,HLA-DQA1,HLA-DRB5 |
| Intestinal i | HLA-DQA1,HLA-DQA2,MADCAM1,HLA-DPB1,HLA-DQB1,CCL25B,Il2,PIGR,CD80,BMA2 |
| Primary i | CD40LG,RAG2,CD3E,RAG1,BLNK,CD40,ORAI1,BTK,IL7R,CD8B1 |
| nodeficiency | IGLL1,CD40LG, Cd79b,CD40,RFX5,DCLRE1C,TNFRSF13B,LCK,ICOS,RFXANK |
Protein Function
AICDA has several biochemical functions, for example, cytidine deaminase activity,protein binding,ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AICDA itself. We selected most functions AICDA had, and list some proteins which have the same functions with AICDA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | POLDIP3,BIK,BUD31,ZFYVE9,THOC7,HOXB5,MED23,JAM3,POGZ,CDCA8 |
| ubiquitin protein ligase binding | HIF1A,FHIT,PINK1,PRKAR1A,LTBR,UBE2J2,CDKN1A,HSPD1,GABARAP,TP53 |
| zinc ion binding | SERPINB1A,PTPN1,BMP1,MYCBP2,ZFYVE19,CECR1,TRIM4,NRAP,TRIM27,MARCH7 |
| cytidine deaminase activity | APOBEC2,APOBEC1,WBP2NL,APOBEC3G,CDA,APOBEC3F,APOBEC3H |
Interacting Protein
AICDA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AICDA here. Most of them are supplied by our site. Hope this information will be useful for your research of AICDA.
TDG;DNAJA2;HSPA8;GADD45A;DNAJA1
Resources
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References
- Kitabatake, M; Soma, M; et al. JNK Regulatory Molecule G5PR Induces IgG Autoantibody-Producing Plasmablasts from Peritoneal B1a Cells. JOURNAL OF IMMUNOLOGY 194:1480-1488(2015).
- Fairfax, KA; Gantier, MP; et al. IL-10 regulates Aicda expression through miR-155. JOURNAL OF LEUKOCYTE BIOLOGY 97:71-78(2015).
