ABCC4
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Official Full Name
ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -
Overview
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. [provided by RefSeq, Jul 2008] -
Synonyms
ABCC4;ATP-binding cassette, sub-family C (CFTR/MRP), member 4;MRP4;MOATB;MOAT-B;EST170205;multidrug resistance-associated protein 4;MRP/cMOAT-related ABC transporter;multispecific organic anion transporter B;ATP-binding cassette sub-family C member 4;multi-specific organic anion transporter B;bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4);canalicular multispecific organic anion transporter (ABC superfamily)
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- E. coli
- Wheat Germ
- Mammalian Cell
- E.coli
- Mammalian cell
- N-His
- N-GST
- GST
- His
- His&T7
- His&StrepII&EGFP
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| OLFML3-1453H | Recombinant Human OLFML3 protein, His-tagged | E. coli | Human | N-His | 57-406 aa | |
| PAX2-1539H | Recombinant Human PAX2 protein, GST-tagged | E. coli | Human | N-GST | 145-432 aa | |
| ABCC4-048H | Recombinant Human ABCC4 Protein, GST-Tagged | Wheat Germ | Human | GST |
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| ABCC4-1621Z | Recombinant Zebrafish ABCC4 | Mammalian Cell | Zebrafish | His |
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| ABCC4-2515C | Recombinant Chicken ABCC4 | Mammalian Cell | Chicken | His |
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| ABCC4-8119H | Recombinant Human ABCC4 protein, His & T7-tagged | E.coli | Human | His&T7 | Ile1041~Gln1274 |
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| ABCC4-0103H | Recombinant Human ABCC4 Protein (M1-L1325), eGFP, Strep II, 10×His tagged | Mammalian cell | Human | His&StrepII&EGFP | M1-L1325 |
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| ABCC4-0104H | Recombinant Human ABCC4 Protein (M1-L1325), eGFP, Strep II, 10×His tagged | Mammalian cell | Human | His&StrepII&EGFP | M1-L1325 |
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| ABCC4-0492H | Recombinant Human ABCC4 Protein (Ile1041-Gln1274), N-His-tagged | E.coli | Human | His | Ile1041-Gln1274 |
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Involved Pathway
ABCC4 involved in several pathways and played different roles in them. We selected most pathways ABCC4 participated on our site, such as ABC transporters, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCC4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| ABC transporters | ABCC3,ABCA8,ABCB1LB,ABCC9,CFTR,ABCB9,ABCD2,ABCB6,ABCB10,ABCB8 |
Protein Function
ABCC4 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ABCC4 itself. We selected most functions ABCC4 had, and list some proteins which have the same functions with ABCC4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
ABCC4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCC4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCC4.
Resources
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References
- Jozefczuk, J; Stachelscheid, H; et al. Molecular Characterization of Cultured Adult Human Liver Progenitor Cells. TISSUE ENGINEERING PART C-METHODS 16:821-834(2010).
- van de Ven, R; de Groot, J; et al. Unimpaired immune functions in the absence of Mrp4 (Abcc4). IMMUNOLOGY LETTERS 124:81-87(2009).
