STAT4
-
Official Full Name
STAT4 signal transducer and activator of transcription 4 -
Synonyms
STAT4;signal transducer and activator of transcription 4
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Chicken
- Sf9 Insect Cell
- Mammalian Cell
- E.coli
- Insect Cells
- Sf21 Insect Cell
- Insect Cell
- Human Cells
- Mammalian cells
- HEK293
- HEK293T
- His
- Non
- His&MBP
- Flag
- His&Fc&Avi
- Myc&DDK
Involved Pathway
STAT4 involved in several pathways and played different roles in them. We selected most pathways STAT4 participated on our site, such as Jak-STAT signaling pathway,Hepatitis B,Inflammatory bowel disease (IBD), which may be useful for your reference. Also, other proteins which involved in the same pathway with STAT4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Inflammatory bowel disease (IBD) | IL12B,MAF,FOXP3,TBX21,IL18RAP,TLR2,H2-AB1,HLA-DRB4,IL2RG,H2-AA |
| Jak-STAT signaling pathway | IL19,CCND1,CISH,CRLF2,IL10RB,Il23a,IL2RA,IL29,PTPN2B,CISHB |
| Hepatitis B | ELK1,FAS,CCNE1,IFNA17,MYD88,TNF,IKBKB,EGR3,CCNA1,AKT1 |
Protein Function
STAT4 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding,protein binding,signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by STAT4 itself. We selected most functions STAT4 had, and list some proteins which have the same functions with STAT4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II regulatory region sequence-specific DNA binding | ETV6,KLF12,CDX1B,PURB,KAT2B,PAX9,RARA,H2AFY2,PHF21B,IKZF5 |
| protein binding | PTPN11,THEG,PRPF4B,IFRD2,FAM167A,FAM164C,CDKN1B,FAM83A,C4orf33,RBP7 |
| signal transducer activity | OLFR510,TAS2R123,MAPKAPK2A,GPR30,CREBBP,DRD7,EDNRAB,V2RX1,TAS2R104,OLFR151 |
| transcription factor activity, sequence-specific DNA binding | MAFBA,ETV5A,ZNF691,SOX6,NR5A2,ZIC1,SP140,JUNBA,RARA,NKX6-1 |
Interacting Protein
STAT4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STAT4 here. Most of them are supplied by our site. Hope this information will be useful for your research of STAT4.
IL12RB2;SH2D1B;CRK;s10a4_human_core-s1-1_dna-probe;LAMTOR5;NMI;q6f051_bacan;pyn2;s100a4_human_gene
STAT4 Related Signal Pathway
Resources
Research Area
Apoptosis Transcription Factors and RegulatorsNegative Regulators of the Jak/STAT Pathway
STAT
Hematopoietic Stem Cell Transcription Factors and Regulators
Th1 Cells
IL-10 Signaling Related Molecules
IL-12 Signaling Related Molecules
Related Services
Related Products
References
