Recombinant Human STAT4 protein, His/MBP-tagged

• Cat.No.: STAT4-339H
• Product Overview: Recombinant Human STAT4(506-748 aa) fused with His/MBP tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His&MBP
• Protein Length: 506-748 aa
• Description: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
• Form: Liquid in PBS
• Purity: SDS-PAGE >90%
• Applications: WB Positive Control
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: STAT4 signal transducer and activator of transcription 4 [ Homo sapiens ]
• Official Symbol: STAT4
• Synonyms: STAT4; signal transducer and activator of transcription 4
• Gene ID: 6775
• mRNA Refseq: NM_001243835
• Protein Refseq: NP_001230764
• MIM: 600558
• UniProt ID: Q14765