Recombinant Mouse Stat4 Protein, Myc/DDK-tagged

• Cat.No.: Stat4-6171M
• Product Overview: Purified recombinant protein of mouse full-length signal transducer and activator of transcription 4 (Stat4), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. Homozygous knockout mice for this gene exhibit reduced inflammation and cytokine production in response to immune challenge. Alternative splicing results in multiple transcript variants.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 85.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Stat4 signal transducer and activator of transcription 4 [ Mus musculus (house mouse) ]
• Official Symbol: Stat4
• Synonyms: STAT4; signal transducer and activator of transcription 4
• Gene ID: 20849
• mRNA Refseq: NM_011487
• Protein Refseq: NP_035617
• UniProt ID: P42228