SPINK1
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Official Full Name
SPINK1 serine peptidase inhibitor, Kazal type 1 -
Synonyms
SPINK1;serine peptidase inhibitor, Kazal type 1;serine protease inhibitor, Kazal type 1;pancreatic secretory trypsin inhibitor;PCTT;PSTI;Spink3;TATI;tumor-associated trypsin inhibitor;serine protease inhibitor Kazal-type 1;TCP
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- Yeast
- Mammalian cells
- GST
- N-Met,N-His
- His
- Non
- His&GST
- His&Fc&Avi
Involved Pathway
SPINK1 involved in several pathways and played different roles in them. We selected most pathways SPINK1 participated on our site, such as Prostate Cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with SPINK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Prostate Cancer | CREB3L1,PIK3R2,GRB2,TCF7L2,INS1,MDM2,NKX3,PDPK1,ERBB2,MAP4K1 |
Protein Function
SPINK1 has several biochemical functions, for example, endopeptidase inhibitor activity,protein binding,serine-type endopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SPINK1 itself. We selected most functions SPINK1 had, and list some proteins which have the same functions with SPINK1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| endopeptidase inhibitor activity | SERPINA1A,ITIH2,CST3,MUG2,PROS1,STFA1,SPINK2,CST14B.1,C4A,UCHL5 |
| protein binding | SDHAF2,DDX3X,CCNE2,MON2,RHOT2,POU1F1,RARA,SHMT2,KIAA0947,SEPT7 |
| serine-type endopeptidase inhibitor activity | TFPI,ITIH6,Serpina1b,SERPINE1,SPINK3,SPINK6,ITIH5,SERPINB5,PI3,PAPLNB |
Interacting Protein
SPINK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPINK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SPINK1.
ctra_bovin
Resources
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References
- Kunju, LP; Carskadon, S; et al. Novel RNA Hybridization Method for the In Situ Detection of ETV1, ETV4, and ETV5 Gene Fusions in Prostate Cancer. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY 22:E32-E40(2014).
- Smith, SC; Palanisamy, N; et al. HOXB13 G84E-related Familial Prostate Cancers A Clinical, Histologic, and Molecular Survey. AMERICAN JOURNAL OF SURGICAL PATHOLOGY 38:615-626(2014).
