SGK3
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Official Full Name
serum/glucocorticoid regulated kinase family, member 3 -
Overview
Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, glucocorticoid, follicle stimulating hormone, osmotic shock, and mineralocort -
Synonyms
SGK3;serum/glucocorticoid regulated kinase family, member 3;serum/glucocorticoid regulated kinase like , SGK2, SGKL;serine/threonine-protein kinase Sgk3;cytokine-independent survival kinase;CISK;SGK2;SGKL;DKFZp781N0293
Recombinant Proteins
- Human
- Mouse
- Chicken
- Zebrafish
- Insect Cells
- E.coli
- Mammalian Cell
- Sf9 Insect Cell
- Human
- Insect Cell
- HEK293
- HEK293T
- His&GST
- His
- GST
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
SGK3 involved in several pathways and played different roles in them. We selected most pathways SGK3 participated on our site, such as FoxO signaling pathway,PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SGK3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| PIK-Akt signaling pathway | TCL1A,HSP90AA1,GH2,THBS4,PPP2R2C,FLT4,FGF11,FGF1,AKT2,ITGB5 |
| FoxO signaling pathway | PRKAG2A,GADD45B,AKT1,Fasl,S1PR4,SGK2A,PRKAG2,G6PC3,MAPK8A,SKP2 |
Protein Function
SGK3 has several biochemical functions, for example, ATP binding,calcium channel regulator activity,chloride channel regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SGK3 itself. We selected most functions SGK3 had, and list some proteins which have the same functions with SGK3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | ATAD5,GAK,MAP2K3,WNK1,ERN2,AMHR2,AK7B,ACSBG1,UCK2,MOS |
| protein serine/threonine kinase activity | RIOK3,PIM2,SMOK3A,AKT2,BCR,LMTK3,PIK3CG,STK31,GM711,ALPK1 |
| phosphatidylinositol binding | SNX5,SNX6,PIK3C2A,PIK3C2G,FCHO2,CCDC88A,ING2,SNX1B,NISCH,SNX7 |
| protein kinase activity | PAK2A,FASTKD1,DCKL1B,MAP3K4,PLK1,NEK10,NPR1,PTK6B,KALRN,OXSR1B |
| calcium channel regulator activity | STIM1A,SGK1,GNB2,CRISP1,SGK2,CACNB2,CACNA2D1A,GRM6A,SRI,PRKG1 |
| potassium channel regulator activity | KCNAB1,SGK2A,CHP,KCNAB2,ARPP19A,KCNIP2,ARPP19,SUMO1,KCNE2,KCNS3 |
| chloride channel regulator activity | SGK2A,SLC9A3R1,SGK2B,CHRNA7,SGK2,SGK1,BSND |
| protein binding | FAM46C,TRIM55,HTR3C,PDS5B,HSPA1L,EPHA2,PKD1,FAM109A,IL7R,KRT25 |
| sodium channel regulator activity | SCN1BA,FGF12,GPLD1,SCLT1,SCN1B,SGK2A,FXYD5,NEDD4L,SGK2,AGT |
Interacting Protein
SGK3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SGK3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SGK3.
ITCH;pi3p;PDK1;HSP90AB1;GSK3B;gatB
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