NPR3
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Official Full Name
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) -
Overview
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity -
Synonyms
NPR3 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C);atrial natriuretic peptide receptor 3;NPRC;ANP-C;ANPRC;NPR-C;ANPR-C;GUCY2B;C5orf23;FLJ14054;MGC22189;OTTHUMP00000161704;OTTHUMP00000197047;OTTHUMP00000197048;OTTHUMP00000220980;OTTHUMP00000226999;atrial natriuretic peptide receptor type C;atrial natriuretic peptide clearance receptor
Recombinant Proteins
- Human
- Mouse
- Rat
- Zebrafish
- Bovine
- Mus musculus
- Wheat Germ
- E.Coli or Yeast
- Mammalian Cell
- E.coli
- HEK293
- Mammalian cells
- HEK293T
- Yeast
- E.coli expression system
- Non
- His
- His&T7
- Flag
- Fc
- His&Fc&Avi
- Myc&DDK
- His&Myc
- GST
- His&SUMO
Involved Pathway
NPR3 involved in several pathways and played different roles in them. We selected most pathways NPR3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NPR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
NPR3 has several biochemical functions, for example, G-protein coupled peptide receptor activity,NOT adenylate cyclase activity,hormone binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NPR3 itself. We selected most functions NPR3 had, and list some proteins which have the same functions with NPR3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NOT adenylate cyclase activity | GUCY2C,NPR1A,GUCY1A3,GUCY1B3,GC3,NPR1,GUCY2F,GC2,NPR2 |
| natriuretic peptide receptor activity | NPR2,NPR1,NPR1A |
| hormone binding | ADIPOR2,UCN2,MC1R,NPR1,CALR,LRP2,AMHR2,NPR2,ADIPOR1A,MC5R |
| G-protein coupled peptide receptor activity | FSHR,GPR84,CYSLTR1,MC1R,RXFP3.2B,NPR1,TSHR,LTB4R2,GRPR,MCHR2 |
| protein homodimerization activity | STK4,CBX1,ROPN1B,HNF1A,CADM3,TSG101,MTUS2,HM13,ATPIF1,BCL2A |
| peptide hormone binding | CRHR2,MC4R,AGTR1B,AGTR1A,SLC40A1,GALR1,AGTR2,EDNRB,PTH1RA,OXTR |
Interacting Protein
NPR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NPR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NPR3.
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