HLF

  • Official Full Name

    hepatic leukemia factor
  • Overview

    This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription;factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds;sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene;with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript;variants have been described, but their biological validity has not been determined.
  • Synonyms

    HLF;hepatic leukemia factor;MGC33822

Recombinant Proteins

  • Human
  • Rhesus macaque
  • E.coli
  • Mammalian Cell
  • Wheat Germ
  • Human
  • HEK293
  • In Vitro Cell Free System
  • His&T7
  • His
  • GST
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
HLF-209H Recombinant Human HLF protein, T7/His-tagged E.coli Human His&T7
HLF-2103R Recombinant Rhesus monkey HLF Protein, His-tagged Mammalian Cell Rhesus macaque His
HLF-27715TH Recombinant Human HLF, His-tagged E.coli Human His 295 amino acids
HLF-3618H Recombinant Human HLF, His-tagged E.coli Human His
HLF-4852H Recombinant Human HLF Protein, GST-tagged Wheat Germ Human GST
HLF-5023H Recombinant Human Hepatic Leukemia Factor, His-tagged Human Human His
HLF-5490HCL Recombinant Human HLF 293 Cell Lysate HEK293 Human Non
HLF-1924R Recombinant Rhesus Macaque HLF Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
HLF-1924R-B Recombinant Rhesus Macaque HLF Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
HLF-3633HF Recombinant Full Length Human HLF Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 295 amino acids

    Involved Pathway

    HLF involved in several pathways and played different roles in them. We selected most pathways HLF participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HLF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    HLF has several biochemical functions, for example, DNA binding,double-stranded DNA binding,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HLF itself. We selected most functions HLF had, and list some proteins which have the same functions with HLF. You can find most of the proteins on our site.

    Function Related Protein
    transcription factor activity, sequence-specific DNA binding IRF6,PHOX2A,AFF4,ETV6,NPAS1,ZNF792,ZFP82,UBN1,CSRNP2,TCF19
    double-stranded DNA binding TRP53,FEV,PNKP,GTF2H4,MEN1,MRE11A,CRY1,TDG,SATB1,DDX58
    DNA binding PRIM2,SRFA,TEAD1,POLE2,NR4A2,RNF6,PPP1R8,NPAS4,TRIM30A,MCM3AP
    sequence-specific DNA binding POU3F3B,DBX2,CREBL2,FOXJ1B,HOXA1,CREB3L3A,NKX3,NKX2.7,IKZF4,GLI2

    Interacting Protein

    HLF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HLF here. Most of them are supplied by our site. Hope this information will be useful for your research of HLF.

    DDIT3;BATF;BATF3;DBP;yfeE;q5nf29_fratt;sbcB;pheS;recJ;gatA;sSL2;mglA10;q81kb5_bacan;moeA1;yndJ;q81un5_bacan;q81up8_bacan;rbsC

    Resources

    References

    • Reeves, SR; Kolstad, T; et al. Fibroblast-myofibroblast transition is differentially regulated by bronchial epithelial cells from asthmatic children. RESPIRATORY RESEARCH 16:-(2015).
    • Shiga, Y; Oshima, Y; et al. Recombinant human lactoferrin-Fc fusion with an improved plasma half-life. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 67:136-143(2015).

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