GABARAPL2
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Official Full Name
GABA(A) receptor-associated protein-like 2 -
Overview
Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. -
Synonyms
GABARAPL2;GABA(A) receptor-associated protein-like 2;gamma-aminobutyric acid receptor-associated protein-like 2;ATG8;ATG8C;GATE 16;GATE16;GEF2;ganglioside expression factor 2;MAP1 light chain 3 related protein;MAP1 light chain 3-related protein
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Rat
- Mouse
- E.coli
- Mammalian Cell
- Human Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- E. coli
- GST
- His
- His&Fc&Avi
Involved Pathway
GABARAPL2 involved in several pathways and played different roles in them. We selected most pathways GABARAPL2 participated on our site, such as Cellular responses to stress,FoxO signaling pathway,GABAergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with GABARAPL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| FoxO signaling pathway | PLK1,S1PR4,USP7,FASLG,FBXO25,MAPK8B,FOXO3B,PTEN,PRKAA1,STAT3 |
| Macroautophagy | ATG9B,WIPI1,DYNLL2B,ATG101,RB1CC1,ATG7,ATG4A,WDR45,GABARAP,ATG9A |
| Senescence and Autophagy | AMBRA1,SLC39A3,ING1,IL24,IGFBP7,SLC39A2,FKBP8,COL10A1,GABARAP,IGFBP5 |
| Regulation of autophagy | ULK1,INS,IFNA10,ATG10,IFNA17,IFNG1-2,PRKAA1,ATG4B,ULK3,IFNA1 |
| Cellular responses to stress | HMGA1,RAD50,HMGA1-RS1,PRDX3,MINK1,CABIN1,C11orf73,DNAJB6,ATG9A,CDK6 |
| GABAergic synapse | GABRA2,GNB4,SLC38A3,GABARAP,GAD2,GABRB1,PRKCG,GNG3,GABRA4,GNGT1 |
Protein Function
GABARAPL2 has several biochemical functions, for example, ATPase binding,GABA receptor binding,SNARE binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GABARAPL2 itself. We selected most functions GABARAPL2 had, and list some proteins which have the same functions with GABARAPL2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| beta-tubulin binding | PACRG,PIFO,HDAC6,VAPB,LRPPRC,FGF13,EMD,OST4,ARL8A,CCT5 |
| ATPase binding | PEX19,NOP58,PGR,ATPIF1,ABCA1,NUFIP1,EZR,GRIN2A,SDF2L1,CAV1 |
| protein binding | SERPINB3C,C1QTNF2,MPLKIP,NEK8,EIF4EBP2,CCNT1,SPI1B,TMCO6,APC,EIF3I |
| microtubule binding | NUMA1,VPS41,MAP4,MAP205,NDRG1,GAS2L1,PAFAH1B1,MAP1LC3B,MAPRE2,CEP57L1 |
| GABA receptor binding | GABARAPA,MAF1,ARFGEF2,GABRB1,TRAK1,JAKMIP1,GABRG1,PLCL1,GABRA5,GABARAP |
| ubiquitin protein ligase binding | HSPA5,JKAMP,DTX1,PRKACA,MC4R,UQCRC1,TRAF4,TRIOBP,PPARGC1A,CUL5A |
| SNARE binding | SEC22BB,STX11A,SYBL1,STX5A,EXOC3L1,VTI1A,STX2,STX5AL,STX1B,LRRK2 |
Interacting Protein
GABARAPL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GABARAPL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GABARAPL2.
SQSTM1;UBA5
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