FUCA1
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Official Full Name
fucosidase, alpha-L- 1, tissue -
Overview
The protein encoded by this gene is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in this gene are associated with fucosidosis (FUCA1D), which is an autosomal recessive lysosomal storage disease. A pseudogene of this locus is present on chr 2. -
Synonyms
FUCA1;fucosidase, alpha-L- 1, tissue;tissue alpha-L-fucosidase;Alpha L fucosidase I;Alpha L fucoside fucohydrolase;Alpha-L-fucosidase 1;Alpha-L-fucosidase I;Alpha-L-fucoside fucohydrolase 1;FUCA;FUCO_HUMAN;Tissue alpha L fucosidase;OTTHUMP00000003009
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Human Cell
- Mammalian cells
- Mammalian Cell
- Wheat Germ
- Insect Cell
- HEK293T
- HEK293
- In Vitro Cell Free System
- GST
- His&Fc
- His
- His&SUMO
- Non
- His&T7
- His&T8
- Myc&DDK
- His&Fc&Avi
Involved Pathway
FUCA1 involved in several pathways and played different roles in them. We selected most pathways FUCA1 participated on our site, such as Other glycan degradation,Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with FUCA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Other glycan degradation | FUCA1.1,MANBA,ENGASE,NEU3.3,NEU4,NEU3.5,FUCA2,MAN2B2,ENG-1,GBA |
| Lysosome | CTSE,ATP6AP1B,CD164,ATP6V0A1B,CTSBB,NAPSA,ASAH1,MANBA,ATP6V0A2B,TPP1 |
Protein Function
FUCA1 has several biochemical functions, for example, alpha-L-fucosidase activity,fucose binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FUCA1 itself. We selected most functions FUCA1 had, and list some proteins which have the same functions with FUCA1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| alpha-L-fucosidase activity | FUCA1.1,FUCA2,FUCA1.2 |
| fucose binding | FUCA2,SELP,FUOM |
Interacting Protein
FUCA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FUCA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FUCA1.
MARK2;USP21;VAV2
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