EIF3E
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Official Full Name
eukaryotic translation initiation factor 3, subunit E -
Overview
Eukaryotic translation initiation factor 3 subunit E is a protein that in humans is encoded by the EIF3E gene. -
Synonyms
EIF3E;eukaryotic translation initiation factor 3, subunit E;EIF3S6, eukaryotic translation initiation factor 3, subunit 6 48kDa , INT6;eukaryotic translation initiation factor 3 subunit E;eIF3 p48;eIF-3 p48;EIF3S6;eIFe;Eukaryotic translation initiation factor 3 subunit 6;INT6;Viral integration site protein INT-6 homolog;OTTHUMP00000227726;OTTHUMP00000227727;mammary tumor-associated protein INT6;murine mammary tumor integration site 6 (oncogene homolog);eukaryotic translation initiation factor 3, subunit 6 48kDa;eukaryotic translation initiation factor 3, subunit 6 (48kD);EIF3-P48;eIF3-p46
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- Rat
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- Mammalian cells
- In Vitro Cell Free System
- HEK293T
- His
- Non
- GST
- Flag
- His&Fc&Avi
- Myc&DDK
Involved Pathway
EIF3E involved in several pathways and played different roles in them. We selected most pathways EIF3E participated on our site, such as RNA transport,Hepatitis C, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF3E were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hepatitis C | EIF2AK4,PPP2R2B,PPP2R2D,CLDN6,IKBKB,BAD,STAT2,PIK3R3,IFNA8,CLDN9 |
| RNA transport | EIF3S10,EIF1AY,GEMIN7,EEF1A1A,EIF2S1B,SENP2,SMN,UPF1,NUP205,ELAC2 |
Protein Function
EIF3E has several biochemical functions, for example, poly(A) RNA binding,protein N-terminus binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF3E itself. We selected most functions EIF3E had, and list some proteins which have the same functions with EIF3E. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| translation initiation factor activity | EIF4BB,EIF5,DHX29,EIF4EB,EIF3BA,EIF1AX,EIF4E1C,EIF4E3,EIF4G1,EIF2S1A |
| contributes_to translation initiation factor activity | EIF3D,EIF3G,EIF2B1,EIF3J,EIF3S6IP,EIF3F,EIF3EB,EIF2B4,EIF3L,EIF3I |
| protein binding | UBA7,TULP3,DTNBP1,ZNF2,CHDH,BNIP3L,CTH,SLC25A10,CEBPA,PABPC1 |
| poly(A) RNA binding | PKM,CAST,HNRNPC,RDBP,SRP72,PTBP2,HERC5,FNDC3A,FAM98C,REXO4 |
| protein N-terminus binding | RASSF1,DCTN4,VPS25,RND2,ARF6,ALOX5AP,HESX1,NFE2,KCNIP2,MAU2 |
Interacting Protein
EIF3E has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF3E here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF3E.
RUNDC3A;TRIM27;EPAS1
Resources
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References
- Suo, JF; Medina, D; et al. Int6 reduction activates stromal fibroblasts to enhance transforming activity in breast epithelial cells. CELL AND BIOSCIENCE 5:-(2015).
- Guinand, B; Quere, N; et al. From the laboratory to the wild: salinity-based genetic differentiation of the European sea bass (Dicentrarchus labrax) using gene-associated and gene-independent microsatellite markers. MARINE BIOLOGY 162:515-538(2015).
