EBI3
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Official Full Name
Epstein-Barr virus induced gene 3 -
Overview
This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells. -
Synonyms
EBI3;Epstein-Barr virus induced gene 3;interleukin-27 subunit beta;IL-27B;IL-27 subunit beta;epstein-Barr virus-induced gene 3 protein homolog;EBI-3;IL-27
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Macaque
- Human Cell
- Mammalian cells
- E.coli
- Wheat Germ
- HEK293
- Human
- Yeast
- Mammalian Cell
- CHO
- In Vitro Cell Free System
- Fc
- His
- Non
- GST
- His&T7
- His&Fc&Avi
- His&GST
Involved Pathway
EBI3 involved in several pathways and played different roles in them. We selected most pathways EBI3 participated on our site, such as mRNA processing, which may be useful for your reference. Also, other proteins which involved in the same pathway with EBI3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| mRNA processing | HNRNPABA,QK,RBMS3,CLK3,D19BWG1357E,ADAM5,HNRNPH1,RBM39,PPM1G,DHX15 |
Protein Function
EBI3 has several biochemical functions, for example, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EBI3 itself. We selected most functions EBI3 had, and list some proteins which have the same functions with EBI3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | EIF4A2,RPUSD3,GLTSCR2,MRPL1,MADD,CLK3,RNPS1,RPS20,UBA1,IFIT5 |
Interacting Protein
EBI3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EBI3 here. Most of them are supplied by our site. Hope this information will be useful for your research of EBI3.
SMAD3;MDFI
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References
- Singh, K; Hjort, M; et al. Concomitant analysis of Helios and Neuropilin-1 as a marker to detect thymic derived regulatory T cells in naive mice. SCIENTIFIC REPORTS 5:-(2015).
- Mitani, A; Niedbala, W; et al. Increased Expression of Interleukin (IL)-35 and IL-17, But Not IL-27, in Gingival Tissues With Chronic Periodontitis. JOURNAL OF PERIODONTOLOGY 86:301-309(2015).
