COL4A1
-
Official Full Name
collagen, type IV, alpha 1 -
Synonyms
COL4A1;collagen, type IV, alpha 1;collagen alpha-1(IV) chain;COL4A1 NC1 domain;collagen IV, alpha-1 polypeptide;collagen of basement membrane, alpha-1 chain;HANAC;POREN1;arresten
Recombinant Proteins
- Mouse
- Chicken
- Human
- Cattle
- Mammalian Cell
- E.coli
- Placenta
- HEK293
- His
- His&S
- His&Fc&Avi
- His&SUMO
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| COL4A1-3735M | Recombinant Mouse COL4A1 Protein | Mammalian Cell | Mouse | His |
|
|
| COL4A1-3967C | Recombinant Chicken COL4A1 | Mammalian Cell | Chicken | His |
|
|
| COL4A1-611H | Recombinant Human COL4A1 protein, His & S-tagged | E.coli | Human | His&S | His1444~Thr1669 |
|
| COL4A1-001H | Native Human COL4A1 Protein | Placenta | Human |
|
||
| COL4A1-1764H | Recombinant Human COL4A1 Protein (His1444-Thr1669), N-His tagged | E.coli | Human | His | His1444-Thr1669 |
|
| COL4A1-1863M | Recombinant Mouse COL4A1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| COL4A1-1863M-B | Recombinant Mouse COL4A1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
||
| COL4A1-2713H | Recombinant Human COL4A1 protein, His-SUMO-tagged | E.coli | Human | His&SUMO | 1445-1669aa |
|
| COL4A1-5269H | Recombinant Human COL4A1 protein, GST-tagged | E.coli | Human | GST | 30-167aa |
|
| COL4A1-819C | Recombinant Cattle COL4A1 Protein, His-tagged | E.coli | Cattle | His | Gly1445-Thr1669 |
|
| Col4a1-820M | Recombinant Mouse Col4a1 Protein, His-tagged | E.coli | Mouse | His | Pro1416-Thr1669 |
|
| Col4a1-821M | Recombinant Mouse Col4a1 protein(1445-1669aa), His-tagged | E.coli | Mouse | His | 1445-1669aa |
|
Involved Pathway
COL4A1 involved in several pathways and played different roles in them. We selected most pathways COL4A1 participated on our site, such as PIK-Akt signaling pathway,Focal adhesion,ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with COL4A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Small cell lung cancer | CCNE1,BCL2L1,TRP53,PIK3CG,FHIT,LAMC1,CASP9,NFKBIA,LAMB4,BIRC2 |
| Protein digestion and absorption | KCNK5,ACE2,KCNJ13,COL7A1,PRSS2,CPA2,MEP1A,PRSS1,COL10A1,CELA3B |
| Amoebiasis | IL1B,IL12A,TGFB2,GNAQ,ACTN2,SERPINB6B,CXCL1,PRKACA,COL4A4,NOS2 |
| Pathways in cancer | BIRC7,PLCB3,WNT7B,PPARD,AKT2,NFKB1,RALB,CTBP2,STAT5B,GSK3B |
| ECM-receptor interaction | ITGA8,Reln,HMMR,COL6A6,COL5A2A,COL24A1,ITGA6B,DAG1,VTNB,COL11A1A |
| PIK-Akt signaling pathway | ANGPT4,PTK2,HSP90AB1,CREB3L3,G6PC3,IL4R,INSR,LAMB3,PKN3,IL3RA |
| Focal adhesion | PAK2A,ACTB2,PAK6,PDGFAB,VAV3,MAPK3,RAC3B,PRKCBB,HRAS,COL5A2A |
Protein Function
COL4A1 has several biochemical functions, for example, extracellular matrix structural constituent,platelet-derived growth factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COL4A1 itself. We selected most functions COL4A1 had, and list some proteins which have the same functions with COL4A1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| extracellular matrix structural constituent | COL11A2,KAL1,ELNA,CD4,MUC5AC,TFPI2,COMP,COL4A4,LAMC1,COL4A5 |
| platelet-derived growth factor binding | COL6A1,PDGFA,COL1A1,COL2A1,COL5A1,PDGFB,COL1A2,COL3A1,Pdgfa&Pdgfb,PDGFRB |
Interacting Protein
COL4A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COL4A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of COL4A1.
Ywhae
Resources
Related Services
Related Products
References
- Chen, SY; Lin, JS; et al. Modulation of tumor cell stiffness and migration by type IV collagen through direct activation of integrin signaling pathway. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 555:1-8(2014).
- Ullah, M; Sittinger, M; et al. Extracellular matrix of adipogenically differentiated mesenchymal stem cells reveals a network of collagen filaments, mostly interwoven by hexagonal structural units. MATRIX BIOLOGY 32:452-465(2013).
