CD82
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Official Full Name
CD82 molecule -
Overview
This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] -
Synonyms
CD82;CD82 molecule;R2;4F9;C33;IA4;ST6;GR15;KAI1;SAR2;TSPAN27;CD82 antigen;tspan-27;C33 antigen;tetraspanin-27;inducible membrane protein R2;metastasis suppressor Kangai-1;kangai 1 (suppression of tumorigenicity 6, prostate;CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4))
Recombinant Proteins
- Human
- Chicken
- Mouse
- Rat
- Mus musculus
- HEK293
- Wheat Germ
- Mammalian Cell
- Human Cell
- E.coli
- In Vitro Cell Free System
- Mammalian cells
- E.coli expression system
- His
- GST
- Non
- His&Fc&Avi
- His&SUMO
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CD82-3969H | Recombinant Human CD82 protein(Gly111-Leu228), His-tagged | HEK293 | Human | His | 111-228 a.a. | |
| CD82-0867H | Recombinant Human CD82 Protein, GST-Tagged | Wheat Germ | Human | GST |
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| CD82-1848C | Recombinant Chicken CD82 | Mammalian Cell | Chicken | His |
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| CD82-27889TH | Recombinant Human CD82 | Wheat Germ | Human | Non | 267 amino acids |
|
| CD82-3111M | Recombinant Mouse CD82 Protein | Mammalian Cell | Mouse | His |
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| CD82-1960HCL | Recombinant Human CD82 cell lysate | Human Cell | Human | Non |
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| CD82-127H | Recombinant Human CD82 protein, His-tagged | E.coli | Human | His | 35-264 aa |
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| CD82-146H | Recombinant Human CD82 Protein, C-His-tagged | E.coli | Human | His |
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| CD82-1470M | Recombinant Mouse CD82 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CD82-1470M-B | Recombinant Mouse CD82 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| Cd82-2674M | Recombinant Mouse Cd82 protein, His-SUMO-tagged | E.coli | Mouse | His&SUMO | 111-227aa |
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| CD82-3070HF | Recombinant Full Length Human CD82 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 267 amino acids |
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| CD82-3721H | Recombinant Human CD82 Protein (Gly111-Leu228), C-His tagged | Mammalian cells | Human | His | Gly111-Leu228 |
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| CD82-3970H | Recombinant Human CD82(Gly103-Gln225) Protein, N-Fc-tagged | HEK293 | Human | Fc | 103-225 a.a. |
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| CD82-67HF | Recombinant Full Length Human CD82 Protein | In Vitro Cell Free System | Human | Full L. 267 amino acids |
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| RFL11281RF | Recombinant Full Length Rat Cd82 Antigen(Cd82) Protein, His-Tagged | E.coli expression system | Rat | His | Full L. Full Length (1-266) |
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| RFL2400MF | Recombinant Full Length Mouse Cd82 Antigen(Cd82) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length (1-266) |
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| RFL30269HF | Recombinant Full Length Human Cd82 Antigen(Cd82) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-267) |
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Involved Pathway
CD82 involved in several pathways and played different roles in them. We selected most pathways CD82 participated on our site, such as Direct p53 effectors,Integrated Pancreatic Cancer Pathway,p53 signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD82 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Integrated Pancreatic Cancer Pathway | LEFTY1,TFF1,PPP1R13L,FST,WRN,MST1,FKBP1B,MAPK4,BRF1,GPRC5A |
| p53 signaling pathway | SESN3,GADD45G |
| Direct p53 effectors | CSE1L,PCBP4,FOXA1,PPM1J,DUSP1,BNIP3L,ZNF385A,GADD45A,AIFM2,PRDM1 |
Protein Function
CD82 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD82 itself. We selected most functions CD82 had, and list some proteins which have the same functions with CD82. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | AP1M1,TP63,SUPV3L1,GPR177,NDUFS3,LDLR,GINS2,COQ9,C14orf135,COMTD1 |
Interacting Protein
CD82 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD82 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD82.
VANGL1;CD19;NFKB1;NUP88;q9wmx2-pro_0000037550
Resources
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References
- Bawa, Z; Routledge, SJ; et al. Functional recombinant protein is present in the pre-induction phases of Pichia pastoris cultures when grown in bioreactors, but not shake-flasks. MICROBIAL CELL FACTORIES 13:-(2014).
- Wang, Q; Wang, L; et al. L-22 enhances the invasiveness of endometrial stromal cells of adenomyosis in an autocrine manner. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY 7:5762-5771(2014).
