CD58

  • Official Full Name

    CD58 Molecule
  • Overview

    Neural Cell Adhesion Molecule (NCAM, also the cluster of differentiation CD56) is a homophilic binding glycoprotein expressed on the surface of neurons, glia, skeletal muscle and natural killer cells. NCAM has been implicated as having a role in cell–cell adhesion, neurite outgrowth, synaptic plasticity, and learning and memory.
  • Synonyms

    lymphocyte function-associated antigen 3;ag3;LFA-3;OTTHUMP00000024363;OTTHUMP00000024364;OTTHUMP00000231922;OTTHUMP00000231923;CD58 antigen, (lymphocyte function-associated antigen 3);Surface glycoprotein LFA-3;CD58 antigen;FLJ23181;LFA3;FLJ43722;CD58;CD58 molecule

Recombinant Proteins

  • Cynomolgus
  • Human
  • Rhesus macaque
  • HEK293
  • Wheat Germ
  • Human
  • E.coli
  • Mammalian Cell
  • Human Cell
  • Mammalian cells
  • Human Cells
  • Insect Cell
  • In Vitro Cell Free System
  • CHO
  • E.coli expression system
  • His
  • Fc
  • His&Fc
  • His&Flag
  • Non
  • GST
  • Flag
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
CD58-1205C Active Recombinant Cynomolgus CD58 Protein, His-tagged HEK293 Cynomolgus His 1-215 a.a.
CD58-543H Active Recombinant Human CD58 protein, hFc-tagged HEK293 Human Fc Met1-Arg215
CD58-1264H Active Recombinant Human CD58 protein, hFc&His-tagged HEK293 Human His&Fc Phe 29 - Arg 215
CD58-005H Recombinant Human CD58 Protein, DDK/His-tagged HEK293 Human His&Flag 29-215 a.a.
CD58-0834H Recombinant Human CD58 Protein Wheat Germ Human Non
CD58-0835H Recombinant Human CD58 Protein, GST-Tagged Wheat Germ Human GST
CD58-348H Recombinant Human CD58 protein, Fc-tagged HEK293 Human Fc 187
CD58-4137H Recombinant Human CD58 Molecule Human Human Non
CD58-462H Recombinant Human CD58 protein, His-tagged HEK293 Human His Phe29-Arg215
CD58-682H Recombinant Human CD58 molecule, His-tagged E.coli Human His 29-215 a.a.
CD58-745R Recombinant Rhesus monkey CD58 Protein, His-tagged Mammalian Cell Rhesus macaque His
CD58-1127HCL Recombinant Human CD58 cell lysate Human Cell Human Non
CD58-797CCL Recombinant Cynomolgus CD58 cell lysate Human Cell Cynomolgus Non
CD58-1240H Recombinant Human CD58 Protein (Met1-Arg215), C-His tagged Mammalian cells Human His Met1-Arg215
CD58-1443H Recombinant Human CD58 Protein (Phe29-His214), N-GST tagged E.coli Human GST Phe29-His214
CD58-151H Recombinant Human CD58 Protein, DYKDDDDK-tagged Human Cells Human Flag
CD58-165H Recombinant Human CD58 Protein, His-tagged HEK293 Human His 240
CD58-166H Recombinant Human CD58 Protein, Fc-tagged HEK293 Human Fc 240
CD58-201H Recombinant Human CD58 Protein, His-tagged E.coli Human His
CD58-246H Recombinant Human CD58 Protein, His-tagged Insect Cell Human His 26-524aa
CD58-3004HF Recombinant Full Length Human CD58 Protein In Vitro Cell Free System Human Full L. 261 amino acids
CD58-3005HF Recombinant Full Length Human CD58 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 240 amino acids
CD58-571R Recombinant Rhesus Macaque CD58 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
CD58-571R-B Recombinant Rhesus Macaque CD58 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
CD58-P058H Recombinant Human CD58, Fc-tagged therapeutic protein(Alefacept) CHO Human Fc
RFL27474HF Recombinant Full Length Human Lymphocyte Function-Associated Antigen 3(Cd58) Protein, His-Tagged E.coli expression system Human His Full L. Full Length of Mature Protein (29-250)

    Involved Pathway

    CD58 involved in several pathways and played different roles in them. We selected most pathways CD58 participated on our site, such as Cell adhesion molecules (CAMs),Epstein-Barr virus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD58 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell adhesion molecules (CAMs) HLA-DQA2,CLDNH,H2-AB1,NLGN3A,CDH1,CLDN4,SDC4,CLDN14,CLDNE,ITGAM
    Epstein-Barr virus infection ENTPD8,NFKBIE,MAP3K14,CR2,EIF2AK3,HLA-DPB1,XPO1,ITGAL,CCNA2,PIK3R5

    Protein Function

    CD58 has several biochemical functions, for example, protein binding,receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD58 itself. We selected most functions CD58 had, and list some proteins which have the same functions with CD58. You can find most of the proteins on our site.

    Function Related Protein
    receptor binding CAT,CXADR,PPY,NPY,C1QTNF2,CSNK2B,MAG,MAP7,MSTN,PVR
    protein binding C6orf211,MYO9B,NLRP12,USP33,TOR1A,KCNA3,MED28,TP53BP1,SOX6,RUNX1T1

    Interacting Protein

    CD58 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD58 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD58.

    PARP2;CD2;DNAJA1;HERPUD1

    Resources

    References

    • Torbati, S; Karami, F; et al. Association of CD58 Polymorphism with Multiple Sclerosis and Response to Interferon ss Therapy in A Subset of Iranian Population. CELL JOURNAL 16:506-513(2015).
    • Raicevic, G; Najar, M; et al. Influence of inflammation on the immunological profile of adult-derived human liver mesenchymal stromal cells and stellate cells. CYTOTHERAPY 17:174-185(2015).

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