CD58
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Official Full Name
CD58 Molecule -
Overview
Neural Cell Adhesion Molecule (NCAM, also the cluster of differentiation CD56) is a homophilic binding glycoprotein expressed on the surface of neurons, glia, skeletal muscle and natural killer cells. NCAM has been implicated as having a role in cell–cell adhesion, neurite outgrowth, synaptic plasticity, and learning and memory. -
Synonyms
lymphocyte function-associated antigen 3;ag3;LFA-3;OTTHUMP00000024363;OTTHUMP00000024364;OTTHUMP00000231922;OTTHUMP00000231923;CD58 antigen, (lymphocyte function-associated antigen 3);Surface glycoprotein LFA-3;CD58 antigen;FLJ23181;LFA3;FLJ43722;CD58;CD58 molecule
Recombinant Proteins
- Cynomolgus
- Human
- Rhesus macaque
- HEK293
- Wheat Germ
- Human
- E.coli
- Mammalian Cell
- Human Cell
- Mammalian cells
- Human Cells
- Insect Cell
- In Vitro Cell Free System
- CHO
- E.coli expression system
- His
- Fc
- His&Fc
- His&Flag
- Non
- GST
- Flag
- His&Fc&Avi
Involved Pathway
CD58 involved in several pathways and played different roles in them. We selected most pathways CD58 participated on our site, such as Cell adhesion molecules (CAMs),Epstein-Barr virus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD58 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Cell adhesion molecules (CAMs) | HLA-DQA2,CLDNH,H2-AB1,NLGN3A,CDH1,CLDN4,SDC4,CLDN14,CLDNE,ITGAM |
Epstein-Barr virus infection | ENTPD8,NFKBIE,MAP3K14,CR2,EIF2AK3,HLA-DPB1,XPO1,ITGAL,CCNA2,PIK3R5 |
Protein Function
CD58 has several biochemical functions, for example, protein binding,receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD58 itself. We selected most functions CD58 had, and list some proteins which have the same functions with CD58. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
receptor binding | CAT,CXADR,PPY,NPY,C1QTNF2,CSNK2B,MAG,MAP7,MSTN,PVR |
protein binding | C6orf211,MYO9B,NLRP12,USP33,TOR1A,KCNA3,MED28,TP53BP1,SOX6,RUNX1T1 |
Interacting Protein
CD58 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD58 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD58.
PARP2;CD2;DNAJA1;HERPUD1
Resources
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References
- Torbati, S; Karami, F; et al. Association of CD58 Polymorphism with Multiple Sclerosis and Response to Interferon ss Therapy in A Subset of Iranian Population. CELL JOURNAL 16:506-513(2015).
- Raicevic, G; Najar, M; et al. Influence of inflammation on the immunological profile of adult-derived human liver mesenchymal stromal cells and stellate cells. CYTOTHERAPY 17:174-185(2015).