CCR1
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Official Full Name
CCR1 chemokine (C-C motif) receptor 1 -
Synonyms
CCR1;chemokine (C-C motif) receptor 1;CMKBR1, SCYAR1;C-C chemokine receptor type 1;CD191;CKR 1;MIP1aR;CCR-1;CC-CKR-1;RANTES-R;C-C CKR-1;MIP-1alpha-R;LD78 receptor;RANTES receptor;macrophage inflammatory protein 1-alpha receptor;CKR1;CKR-1;HM145;CMKBR1;SCYAR1
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Macaca mulatta
- Schizosaccharomyces pombe
- Mus musculus
- E.coli
- HEK293
- Wheat Germ
- Mammalian Cell
- E. coli
- In vitro E. coli expression system
- In Vitro Cell Free System
- E.coli expression system
- His
- Flag
- Non
- GST
- His&Fc&Avi
- N-His-SUMO
Involved Pathway
CCR1 involved in several pathways and played different roles in them. We selected most pathways CCR1 participated on our site, such as Chemokine receptors bind chemokines,Chemokine signaling pathway,Class A/1 (Rhodopsin-like receptors), which may be useful for your reference. Also, other proteins which involved in the same pathway with CCR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Chemokine receptors bind chemokines | CCL35.2,ACKR4,CCR3,CCR6,CXCL11.8,CCL19A.2,CCR9,CXCR7B,CCRL2,AMCF-II |
| Cytokine-cytokine receptor interaction | CCR10,ACKR3B,FLT3,IL17RB,IL20RB,THPO,BMPR1B,CLCF1,CCL16,CCR3 |
| GPCR downstream signaling | RGS18,PROK2,CCR7,LPAR1,S1PR3,CCR8,TRPC6A,OPN1LW1,DRD4,PENKA |
| Chemokine signaling pathway | PIK3CG,CXCL6,SRC,Ccl21c,PIK3CA,CCL23,CXCR6,CXCL2,CXCL13,CCR5 |
| Class A/1 (Rhodopsin-like receptors) | CHRM3,ADORA2B,LPAR1,EDN1,ZFPM2B,FPR-RS4,CCL27,PNOCB,S1PR1,HEBP1 |
| GPCR ligand binding | KEL,ACKR4,CXCL11.8,CX3CR1,QRFPR,PTHLHA,NPS,CRHR1,PMCH,PTH2 |
| G alpha (i) signalling events | CXCL11.8,NMUR1,OXGR1A.2,AGT,APPA,HCAR1-2,RGS11,CHRM4,RGS7,OPN1SW1 |
| GPCRs, Class A Rhodopsin-like | GPR27,DRD4,SSTR4,APLNR,GPR18,GPR68,OPN4,GPR85,GPR17,AGTR2 |
Protein Function
CCR1 has several biochemical functions, for example, C-C chemokine binding,C-C chemokine receptor activity,chemokine (C-C motif) ligand 5 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCR1 itself. We selected most functions CCR1 had, and list some proteins which have the same functions with CCR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chemokine (C-C motif) ligand 5 binding | CCR5 |
| chemokine receptor activity | CXCR4A,CXCR4B,GPR17,CCR5,CX3CR1,CXCR3,CCR6A,CCR6,CCR9,ACKR4 |
| protein binding | YRDC,GRM2,ERAP1,NKX2,LDB3,NEUROD1,CHMP4A,ATF6B,EHD2,EZR |
| C-C chemokine binding | CCR5,DARC,CCBP2,ZFP36 |
| phosphatidylinositol phospholipase C activity | PLCH2,EDNRA,PLCE1,CHRM1,PLCB3,BDKRB2,PLCD1A,PLCG1,PLCL1,PLCD1 |
| C-C chemokine receptor activity | CCBP2,CCR3,CCR1L1,CCR8,CCR9,CCR10,GPR75,CCR6,CCR5,CCR7 |
Interacting Protein
CCR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCR1.
CREB3;PLP2;rpoB
Resources
Research Area
Chemokine ReceptorsNegative Regulators of the Jak/STAT Pathway
Receptors in the Jak/STAT Pathway
T Cell Migration
Monocyte Markers
Th1 Cells
CC Chemokine Receptors
Related Services
Related Products
References
- Asquith, DL; Bryce, SA; et al. Targeting cell migration in rheumatoid arthritis. CURRENT OPINION IN RHEUMATOLOGY 27:204-211(2015).
- Gouwy, M; De Buck, M; et al. Serum amyloid A chemoattracts immature dendritic cells and indirectly provokes monocyte chemotaxis by induction of cooperating CC and CXC chemokines. EUROPEAN JOURNAL OF IMMUNOLOGY 45:101-112(2015).
Reviews
Q&As
This protein is stable after storage at: -20°C to -70°C for 12 months in a lyophilized state; and -70°C for 3 months under sterile conditions after reconstitution.