ATP5H
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Official Full Name
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d -
Overview
Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the d subunit of the Fo complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. In addition, three pseudogenes are located on chromosomes 9, 12 and 15. -
Synonyms
ATP5H;ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d;ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d;ATP synthase subunit d, mitochondrial;ATP5JD;ATPQ;mitochondrial;ATP synthase subunit d;ATP5H_HUMAN;ATPase subunit d;MS504;My032 protein;ATP synthase D chain, mitochondrial;ATP synthase, H+ transporting, mitochondrial F1F0, subunit d
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rat
- Rhesus macaque
- E.coli
- Mammalian Cell
- E.Coli or Yeast
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- HEK293T
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
ATP5H involved in several pathways and played different roles in them. We selected most pathways ATP5H participated on our site, such as Alzheimers disease,Electron Transport Chain,Formation of ATP by chemiosmotic coupling, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP5H were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Alzheimers disease | PLCB2,MAPK1,NDUFB8,NDUFA4,APBB1,NDUFC2,CALML5,UQCR10,COX6A2,RYR3 |
| Electron Transport Chain | COX17,ATPIF1,COX7C,COX8A,SLC25A14,COX4I1,NDUFC2-KCTD14,COX6B1,ATP5S,COX6A1 |
| Formation of ATP by chemiosmotic coupling | ATP5S,ATP5L |
| Metabolic pathways | MTMR3,ALG1,POLR1D,PIGF,GLULB,AGPAT4,CYP4F3,ST3GAL2,MVK,PI4KAA |
| Oxidative phosphorylation | MT-ND4,NDUFA4,NDUFA2,COX6B2,UQCR10,ATP6AP2,Atp5k,ATP6V0D2,ATP6V0CB,ATP6V0CA |
| Huntingtons disease | POLR2H,POLR2F,UQCRQ,CASP9,NDUFB6,NDUFV2,COX7C,SDHA,HIP1,NDUFB10 |
| Parkinsons disease | NDUFA12,ATP5J,ATP5D,COX7B2,LRRK2,NDUFC2,UBA7,NDUFB4,UQCRC1,SNCA |
| Metabolism | CYP4T8,MARCKSB,AKAP5,APOBB.1,CA13,DPEP1,SCP2B,PPM1LA,LYRM4,ITPKA |
Protein Function
ATP5H has several biochemical functions, for example, contributes_to ATPase activity,hydrogen ion transmembrane transporter activity,transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP5H itself. We selected most functions ATP5H had, and list some proteins which have the same functions with ATP5H. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| contributes_to ATPase activity | MSH2,PPP2R4,ATP5C1,RFC3,SFRP5,ATP5O,ATP5L,ATP5J2,ABCG8,ATP5A1 |
| hydrogen ion transmembrane transporter activity | ATP6V0E2,ATP6V1B2,mt-Atp8,ATP6V0D2,SLC46A1,ATP6V0E,ATP5I,ATP5L,ATP6V0A1B,ATP5S |
| transmembrane transporter activity | RALBP1,SLC17A9B,ATP5D,ATP5C1,ATP5L,SLC2A3A,ATP5A1,SLC22A20,SLC2A11L,SV2A |
Interacting Protein
ATP5H has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP5H here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP5H.
ATP5F1;GET4;ssrna_ug;Kcnk1;vpu;USF1;ACKR3;CENPA;BLK;Atp5a1;ICT1;TMEM63B;P;SLC36A1;Tnpo1;Ercc6l;SLC38A9;FAM134A;TM9SF4
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