AIF1
-
Official Full Name
allograft inflammatory factor 1 -
Overview
This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008] -
Synonyms
AIF1;allograft inflammatory factor 1;IBA1;IRT1;AIF-1;IRT-1;protein G1;interferon gamma responsive transcript;ionized calcium-binding adapter molecule 1;allograft inflammatory factor-1 splice variant Hara-1
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- Bovine
- Pig
- E.coli
- Mammalian Cell
- E.Coli or Yeast
- Wheat Germ
- HEK293
- Yeast
- HEK293T
- In Vitro Cell Free System
- His
- Non
- GST
- His&Myc
- His&Fc&Avi
- Fc
- His&SUMO
- His&GST
- Myc&DDK
Involved Pathway
AIF1 involved in several pathways and played different roles in them. We selected most pathways AIF1 participated on our site, such as Spinal Cord Injury, which may be useful for your reference. Also, other proteins which involved in the same pathway with AIF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Spinal Cord Injury | PTPRZ1,NOX4,RGMA,KLK8,LILRB3,LGALS3,RTN4,TNFSF13B,GAP43,OMG |
Protein Function
AIF1 has several biochemical functions, for example, actin filament binding,calcium ion binding,molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by AIF1 itself. We selected most functions AIF1 had, and list some proteins which have the same functions with AIF1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | PCDHB7,MASP2,GUCA1D,PVALB2,CABP1,CABP2,CALM4,MMP24,ANXA9,CANT1 |
| molecular_function | ZBTB26,SLC25A30,TUSC2B,CFAP58,AGFG2,DENR,GLI4,MUC12,ASCL5,TP53TG5 |
| actin filament binding | DBNLA,SYNE1,ARPC1A,FLNC,MYH3,MARCKS,WIPF2B,MYH10,SMYHC2,DBNLB |
Interacting Protein
AIF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AIF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AIF1.
HSFY1;PHB
Resources
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References
- Xu, T; Xie, JS; et al. Allograft Inflammatory Factor 1 Functions as a Pro-Inflammatory Cytokine in the Oyster, Crassostrea ariakensis. PLOS ONE 9:-(2014).
- Wang, L; Zhou, L; et al. Interactome Profile of the Host Cellular Proteins and the Nonstructural Protein 2 of Porcine Reproductive and Respiratory Syndrome Virus. PLOS ONE 9:-(2014).
