Recombinant Yeast Glutaredoxin 2, His-tagged
Cat.No. : | GRX2-76Y |
Product Overview : | Recombinant cerevisiae Glutaredoxin-2 Saccharamyces conaining 6x His-tagged at C-terminus produced inE.Coliis a single, non-glycosylated, Polypeptide chain having a molecular mass of 17 kDa. |
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Species : | Yeast |
Source : | E.coli |
Tag : | His |
Description : | GRX2 is a multifunctional enzyme with glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase (GST) activity. The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing cytosolic protein- and non-protein-disulfides in a coupled system with glutathione reductase. Required for resistance to reactive oxygen species (ROS) by directly reducing hydroperoxides and for the detoxification of ROS-mediated damage. Glutaredoxins are a family of glutathione-dependent hydrogen donors that participate in a variety of cellular redox reactions. |
Physical Appearance : | Sterile Filtered clear colorless solution. |
Purity : | Purity of GRX2 is greater than 90% as determined by SDS-PAGE. |
Formulation : | Glutaredoxin-2 solution contains 25 mM Tris-HCl pH-7.5 & 0.01% Na Azide. |
Applications : | ELISA, Western Blot, strongly binds to glutathione, reduced and oxidized. |
Stability : | 1 week at 2-10°C. For long term store at -20 to -80°C. |
Gene Name | GRX2 Cytoplasmic glutaredoxin, thioltransferase, glutathione-dependent disulfide oxidoreductase involved in maintaining redox state of target proteins, also exhibits glutathione peroxidase activity, expression induced in response to stress [ Saccharomyces cerevisiae ] |
Synonyms | TTR1; Cytoplasmic glutaredoxin, thioltransferase, glutathione-dependent disulfide oxidoreductase involved in maintaining redox state of target proteins, also exhibits glutathione peroxidase activity, expression induced in response to stress; YDR513W; GRX2 |
Gene ID | 852124 |
Protein Refseq | NP_010801 |
UniProt ID | GDBY |
Chromosome Location | IV; |
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GLRX2-5547H | Recombinant Human GLRX2 Protein, Myc/DDK-tagged, C13 and N15-labeled | +Inquiry |
GLRX2-5347HF | Recombinant Full Length Human GLRX2 Protein, GST-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
GLRX2-714HCL | Recombinant Human GLRX2 cell lysate | +Inquiry |
Not For Human Consumption!
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