Recombinant West Nile Virus NS1 Protein, His tagged

• Cat.No.: NS1-133W
• Product Overview: Recombinant West Nile Virus NS1 protein produced in mammalian HEK293 human cells, incorporating a C-terminal 6x His-tag.
  West Nile Virus NS1 protein (Uniprot Q9Q6P4, strain NY99; aa792-114) produced from HEK293 cells.

Specification

• Species: West Nile Virus, strain NY99
• Source: HEK293
• Tag: His
• Protein Length: 792-1143 aa
• Description: The West Nile Virus (WNV) NS1 protein is a native hexameric presentation. The hexamer is believed to be the biologically active form of NS1 involved in key aspects of West Nile Fever pathogenesis (Kaiser et al., 2017). The resultant WNV NS1 protein is purified to a high degree, is in its native folding state, and possesses all post-translational modifications. This advanced approach results in a product which delivers optimal antigenicity by virtue of its human originThe West Nile Virus NS1 Protein has been manufactured in response to the unmet need for a highly purified, concentrated protein for use in further vaccine development and serological based diagnostic assays. The detection of the NS1 protein offers much higher fidelity across multiple flaviviruses where cross-reactivity can otherwise pose an issue.
• Source: HEK293
• Species: West Nile Virus, strain NY99
• Tag: C-6×His
• Form: Liquid
• Purity: Greater than 95% purity by SDS-PAGE.
• Stability: Stable for 1 year at +4 centigrade; stable for 1 year at <-20 centigrade.
  Freezing: Can be frozen
• Storage: Short Term Storage: +4 centigrade
  Long Term Storage: -80 centigrade
• Storage Buffer: DPBS pH 7.4, 0.2 μm filter sterilised.
• Reference: 1. Kaiser et al. (2017). Virulence determinants of West Nile virus: how can these be used for vaccine design? Future Virol. 12(5):283-295.

Gene Information

• Official Symbol: NS1
• Synonyms: NS1; Genome polyprotein; GP1; EC:3.4.21.91
• UniProt ID: Q9Q6P4