Recombinant Rotavirus VP6 Protein

• Cat.No.: VP6-01R
• Product Overview: Astrovirus capsid recombinant protein without tag was expressed and purified from Escherichia coli.

Specification

• Species: Rotavirus
• Source: E.coli
• Description: Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices. This capsid constitutes the middle concentric layer of the viral mature particle. The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus. Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes. VP6 is required for the transcription activity of the DLP.
• Form: Liquid, Clear
• Purity: > 90%
• Storage: Short term storage at 2-8 centigrade. Long term storage at -20 centigrade. Avoid multiple/freeze thaw cycles by storing multiple aliquots at -20 centigrade.
• Storage Buffer: Tris buffer with additives and salts. pH 7.5; 0.09% Sodium azide (NaN3)

Gene Information

• Gene Name: VP6 major inner capsid protein [ Rotavirus C ]
• Official Symbol: VP6
• Synonyms: VP6; major inner capsid protein; major inner capsid protein
• Gene ID: 3773139
• Protein Refseq: YP_392512
• UniProt ID: P69481