Recombinant Rat Ugt1a1 Protein, His-tagged

• Cat.No.: Ugt1a1-535R
• Product Overview: Recombinant Rat Ugt1a1 Protein (Ile62-Ala170) with N-His tag was expressed in E. coli.

Specification

• Description: Enables enzyme binding activity and glucuronosyltransferase activity. Involved in several processes, including biphenyl catabolic process; cellular glucuronidation; and cellular response to lipid. Located in endoplasmic reticulum. Part of cytochrome complex. Used to study Crigler-Najjar syndrome and bilirubin metabolic disorder. Biomarker of hyperthyroidism; type 1 diabetes mellitus; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; female reproductive organ cancer (multiple); and hepatitis B. Orthologous to human UGT1A1 (UDP glucuronosyltransferase family 1 member A1).
• Source: E. coli
• Species: Rat
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 15.9 kDa
  Accurate Molecular Mass: 14 kDa
• Protein length: Ile62-Ala170
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Ugt1a1
• Synonyms: UGT1A1; UDP glucuronosyltransferase 1 family, polypeptide A1; UDP-glucuronosyltransferase 1-1; B1; UGT1*1; UGT1.1; UGT1-01; UDP-glucuronosyltransferase 1A1; UDP-glucuronosyltransferase 1 family member 1; UDP glycosyltransferase 1 family, polypeptide A1; Ugt1; Udpgt; UDPGT 1-1
• Gene ID: 24861
• mRNA Refseq: NM_012683
• Protein Refseq: NP_036815
• UniProt ID: Q64550