Recombinant Rat Tap1, His-tagged

• Cat.No.: Tap1-3511R
• Product Overview: Antigen peptide transporter 1 (Tap1)

Specification

• Species: Rat
• Source: E.Coli/Yeast
• Tag: His
• Protein Length: 725
• Description: has similarity to multidrug resistant transporters; may transport antigenic peptides across the endoplasmic reticulum membrane in preparation for MHC class I presentation .
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Purity: >90%
• Notes: Small volumes of Tap1 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) [ Rattus norvegicus ]
• Official Symbol: Tap1
• Synonyms: Cim; Tap2; Abcb2; antigen peptide transporter 1; APT1; peptide transporter TAP1; transporter 1 ABC (ATP binding cassette); ATP-binding cassette sub-family B member 2; transporter 1 ATP-binding cassette sub-family B
• Gene ID: 24811
• mRNA Refseq: NM_032055
• Protein Refseq: NP_114444
• UniProt ID: P36370
• Chromosome Location: 20p12
• Pathway: ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Herpes simplex infection, organism-specific b
• Function: ADP binding; ADP binding; ADP binding; ATP binding; ATP binding; ATP binding; ATPase activity; ATPase activity; ATPase activity, coupled to transmembrane movement of substances; MHC class I protein binding; MHC class I protein binding; MHC class I protein binding; TAP1 binding; TAP2 binding; TAP2 binding; nucleotide binding; nucleotide binding; oligopeptide-transporting ATPase activity; Contributes_to peptide antigen binding; peptide antigen-transporting ATPase activity; peptide transporter activity; peptide transporter activity; contributes_to peptide transporter activity; protein heterodimerization activity; protein homodimerization activity; tapasin binding; tapasin binding; transporter activity